Intraosseous Epidermoid Cyst Discovered in the Distal Phalanx of a Thumb: A Case Report

Shin, John; Kwon, Ki-Yeon; Oh, Jiwoong

doi:10.1142/s0218810414720241

Cited by 8 publications

(9 citation statements)

References 5 publications

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“…Intraosseous epidermal cysts (IECs) are infrequent nonneoplastic lesions, also termed 'intraosseous epidermoid cysts' or 'keratinous' or 'squamous epithelial cysts'. IECs are lytic bone lesions with sclerotic margins, and can be difficult to differentiate from other tumors or infectious foci [2][3][4]. Histological examination is required for definitive diagnosis; thus, IECs tend to be misdiagnosed and under-reported [1,5].…”

Section: Introductionmentioning

confidence: 99%

An intraosseous epidermal cyst developing in a metacarpal bone after K-wire fixation: a case report

et al. 2015

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Intraosseous epidermal cysts (IECs) are rare benign lesions caused by the proliferation of epidermal cells within the bone. The pathogenesis of IEC remains unclear; however, trauma-triggered infiltration of the bone by epidermal elements has been suggested. Here, we present a case of an IEC in the metacarpal bone of the little finger associated with K-wire fixation for treatment of a fifth metacarpal fracture.

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Section: Introductionmentioning

confidence: 99%

An intraosseous epidermal cyst developing in a metacarpal bone after K-wire fixation: a case report

et al. 2015

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“…The typical manifestation of IEpC in finger is 'clubbing finger'. According to relevant reports of epidermal cyst 4,[6][7][8] , our patient's 'clubbing finger' is the most typical and the patient's 40-year history is very rare. The imaging findings of IEpC are typically welldefined osteolytic lesions with or without soft tissue swelling.…”

Section: Discussionmentioning

confidence: 90%

Intraosseous epidermal inclusion cyst of the right ring finger for 40 years

et al. 2022

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Introduction. Intraosseous epidermal inclusion cysts (IEpC) are benign bone lesions lined with squamous epithelium. Finger phalanges are the second most common site of predilection after skull. Case Report. We present a case of a typical IEpC at the distal phalanx of the right ring finger following a remote history of crush injury to the finger.The patient underwent distal phalanx amputation of the right ring finger. At follow-up 2 years later, the stump healed well and without recurrence. Conclusion. IEpC with a history of up to 40 years is very rare, and although the patient presents with a typical "clubbing finger", the diagnosis was eventually confirmed by surgery and pathology.

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“…Subungual intraosseous epidermoid cysts affecting the distal phalanx are rare lesions reported in humans, dogs and horses . In all species, these lesions are usually considered to be reactive or post‐traumatic pseudotumors .…”

Section: Discussionmentioning

confidence: 99%

Nail abnormalities identified in an ageing study of 30 inbred mouse strains

Mustonen

Silva

Kennedy

et al. 2018

Experimental Dermatology

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In a large-scale ageing study, 30 inbred mouse strains were systematically screened for histologic evidence of lesions in all organ systems. Ten strains were diagnosed with similar nail abnormalities. The highest frequency was noted in NON/ShiLtJ mice. Lesions identified fell into two main categories: acute to chronic penetration of the third phalangeal bone through the hyponychium with associated inflammation and bone remodelling or metaplasia of the nail matrix and nail bed associated with severe orthokeratotic hyperkeratosis replacing the nail plate. Penetration of the distal phalanx through the hyponychium appeared to be the initiating feature resulting in nail abnormalities. The accompanying acute to subacute inflammatory response was associated with osteolysis of the distal phalanx. Evaluation of young NON/ShiLtJ mice revealed that these lesions were not often found, or affected only one digit. The only other nail unit abnormality identified was sporadic subungual epidermoid inclusion cysts which closely resembled similar lesions in human patients. These abnormalities, being age-related developments, may have contributed to weight loss due to impacts upon feeding and should be a consideration for future research due to the potential to interact with other experimental factors in ageing studies using the affected strains of mice.

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Intraosseous Epidermoid Cyst Discovered in the Distal Phalanx of a Thumb: A Case Report

Cited by 8 publications

References 5 publications

An intraosseous epidermal cyst developing in a metacarpal bone after K-wire fixation: a case report

An intraosseous epidermal cyst developing in a metacarpal bone after K-wire fixation: a case report

Intraosseous epidermal inclusion cyst of the right ring finger for 40 years

Nail abnormalities identified in an ageing study of 30 inbred mouse strains

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