Intrapancreatic Accessory Spleen Mimicking Neuroendocrine Tumor on 68Ga-DOTATATE PET/CT

Metzger, Jürg; Keller, Franziska Aebersold; Zander, Andrea; Lago, Marisol Pérez; Herring, Kerstin; Strobel, Klaus

doi:10.1097/rlu.0000000000000863

Cited by 13 publications

(11 citation statements)

References 8 publications

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“…Для уточнения диагноза необходимо выполнение МРТ, а в отдельных случаях и тонкоигольной биопсии под контролем УЗИ. При МРТ измеряемые коэффициенты диффузии ДС и основного органа совпадают [5][6][7][8][9].…”

Section: Discussionunclassified

Intrapancreatic accessory spleen

Kriger¹,

Gorin²,

Калдаров³

et al. 2018

Khir. Z. im. N.I. Pirogova

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Section: Discussionunclassified

Intrapancreatic accessory spleen

Kriger¹,

Gorin²,

Калдаров³

et al. 2018

Khir. Z. im. N.I. Pirogova

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“…Literature documents many case reports of false positives on PET-CT NETSPOT due to ectopic splenic anomalies [12][13][14][15][16][17]. One case report with a literature review showed that 66.7% of patients with intrapancreatic accessory spleen ended up undergoing unnecessary pancreatic resections [13].…”

Section: Discussionmentioning

confidence: 99%

Intrapancreatic Accessory Spleen Diagnosed As Neuroendocrine Tumor: The Dangers of False Positives and Their Implications in Subsequent Management

Kripalani

Patel

Joneja

et al. 2021

Cureus

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This case serves as a reminder to consider ectopic splenic tissue in the differential diagnosis of pancreatic masses. The literature shows a lack of awareness and overtreatment of this condition due to clinical and radiologic concern for malignancy, namely neuroendocrine tumors (NETs) identified on positron emission tomography (PET)-CT NETSPOT. Given the vast difference in management and prognosis of ectopic splenic anomalies and malignant neoplasms involving the pancreas, accurate diagnosis is imperative to avoid unnecessary invasive procedures such as Whipple or distal pancreatectomy and splenectomy, which are associated with increased morbidity and mortality.

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“…The second case was a patient previously splenectomised for trauma that had a second trauma with an injured accessory spleen; in this case, the diagnosis was made on CT scan. Thirteen patients in our study underwent CT scan for diagnosis; in addition, other different diagnostic methods, including US [36], MRI [37] and PET [38] were used. One patient underwent only US, and another underwent only MRI.…”

Section: Discussionmentioning

confidence: 99%

An extremely rare case of an oversized accessory spleen: case report and review of the literature

et al. 2019

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Background The accessory spleen is a congenital defect characterized by a separated ectopic splenic parenchyma. The size is rarely more than 4 cm. The preoperative diagnosis is prohibitive preoperatively. The aims of the present manuscript were to present the case of a patient with a rare oversize accessory spleen and a review of the literature. Case presentation A 15-year-old boy was admitted to the emergency department following blunt abdominal trauma. The computed tomographic scan showed a traumatic rupture of the spleen and a 7-cm mass at the left side of the retroperitoneal space. Conservative treatment started and aborted after 4 h due to the onset of haemodynamic instability. Splenectomy was performed. An accessory spleen was discovered. A second large mass in the retroperitoneum was diagnosed as a second large accessory spleen that was also left in place. The postoperative course was uneventful, and the patient was discharged on the 7th postoperative day. Seven months later, the CT scan showed viability of both accessory spleens. Conclusion An accessory spleen can be variously located and the retroperitoneal position is extremely uncommon. Preoperative diagnosis is still difficult, especially in emergency and as in our case, the literature shows the difficulty of reaching a diagnosis before surgery. The main misdiagnosis is neoplastic disease and for this reason accessory spleen can be wrongly removed. An undiagnosed pre or intra operative retroperitoneal mass, closely to the spleen, have to be managed carefully. The diagnosis of accessory spleen needs to be ever considered as if found, represents a great possibility to conduct a normal life after splenectomy (of main spleen) for trauma.

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Intrapancreatic Accessory Spleen Mimicking Neuroendocrine Tumor on 68Ga-DOTATATE PET/CT

Cited by 13 publications

References 8 publications

Intrapancreatic accessory spleen

Intrapancreatic accessory spleen

Intrapancreatic Accessory Spleen Diagnosed As Neuroendocrine Tumor: The Dangers of False Positives and Their Implications in Subsequent Management

An extremely rare case of an oversized accessory spleen: case report and review of the literature

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