Intrapartum transcervical amnioinfusion for meconium-stained amniotic fluid

“…20 Although biochemical evidence of chorioamnionitis was reduced in amnioinfusion group, but the cause of chorioamnionitis whether as a result of ruptured membranes or due to amnioinfusion itself could not be justified.…”

Section: Jsafogmentioning

confidence: 92%

The Effect of Transabdominal Amnioinfusion on Perinatal Outcomes in Preterm Premature Rupture of Membranes

Tasnim¹,

Mahmud²,

Fatima³

2014

Journal of South Asian Federation of Obstetrics and Gynaecology

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Objective: To evaluate the role of transabdominal amnioinfusion in improving the latency period and perinatal outcomes of pregnancies complicated by preterm premature rupture of membranes (PPROM). Materials and methods:A randomized controlled trial was carried out at MCH Centre, Unit I, PIMS, Islamabad, from Jan 2008 to Dec 2008. Sixty women with singleton pregnancies between 28 and 32 completed weeks of gestation, complicated with PPROM was randomly allocated into two groups viz transabdominal amnioinfusion (amnioinfusion group) and expectant management (control group), within 24 hours of admission. Results:The demographic characteristics were comparable in both the groups. Amnioinfusion group showed significant improvement in PPROM to delivery interval (18.47 ± 6.699 vs 8.93 ± 4.741 days; p = 0.001), neonatal birth weight (p = 0.019) and Apgar scores at 1 and 5 minutes (p = 0.007 for 1 minute and p = 0.012 for 5 minutes). There was less frequency of respiratory distress syndrome (p = 0.032), neonatal sepsis (p = 0.020) and neonatal jaundice (p = 0.002) in the amnioinfusion group. Fewer neonates were admitted to NICU (p = 0.010) and higher survival rate was found in amnioinfusion group (p = 0.023). Conclusion:The treatment with transabdominal amnioinfusion in pregnancies complicated with PPROM resulted in significant prolongation of pregnancy and better neonatal outcomes as compared to women who were managed with traditional expectant management.

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“…[11][12][13][14][15][16] The present study was designed to test the hypothesis that amnioinfusion can reduce the incidence of caesarean deliveries and perinatal morbidity associated with meconium stained amniotic fluid.…”

Section: Introductionmentioning

confidence: 99%

Utility of amnioinfusion in deliveries complicated by meconium stained liquor: a randomized controlled trial

Elsersy

2016

Int J Reprod Contracept Obstet Gynecol

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Background: Meconium stained amniotic fluid could be seen in 12-16 % of deliveries. Meconium is toxic to the newborn lung. Its presence during labour increases the risk to develop neonatal respiratory distress by about 100 times more. Meconium aspiration syndrome (MAS) occurs in about 5% of deliveries with meconium-stained amniotic fluid and death occurs in about 12% of infants with MAS. Intrapartum amnioinfusion was described as a way to dilute meconium or act as a mechanical cushioning of the umbilical cord to prevent its compression .The aim of this study is to perform a randomized controlled clinical trial to test the hypothesis that amnioinfusion can reduce the incidence of caesarean deliveries and perinatal morbidity associated with meconium stained amniotic fluid.Methods: An interventional randomized study was conducted in Hai Jamaa hospital. 360 patients were enrolled in the study. The patients were in labour with meconium stained liquor above 37 weeks. They were randomly allocated in two groups. Group 1: amnioinfusion group and Group 2: non amnioinfusion group.Results: Significant reduction of cesarean section rate due to fetal distress. Also significant reduction of prevalence of variable fetal heart rate decelerations, and significant reduction of incidence of MAS in patients received amnioinfusion.Conclusions: Amnioinfusion is an easy, safe and inexpensive procedure useful in patients with meconium stained liquor.

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Intrapartum transcervical amnioinfusion for meconium-stained amniotic fluid

Abstract: Intrapartum amnioinfusion for MSAF is a simple, safe, effective, and inexpensive procedure feasible in settings where intrapartum monitoring is limited. It is associated with improved perinatal outcome and could lower cesarean delivery rates in low-resource countries.

Cited by 13 publications

References 19 publications

Obstetric care in low-resource settings: What, who, and how to overcome challenges to scale up?

Obstetric care in low-resource settings: What, who, and how to overcome challenges to scale up?

The Effect of Transabdominal Amnioinfusion on Perinatal Outcomes in Preterm Premature Rupture of Membranes

Utility of amnioinfusion in deliveries complicated by meconium stained liquor: a randomized controlled trial

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