Intraperitoneal Instillation of Bupivacaine for Reduction of Postoperative Pain After Laparoscopic Hysterectomy: A Double-Blind Randomized Controlled Trial

Arden, D.; Seifert, Erin L.; Donnellan, Nicole; Guido, Richard S.; Lee, Ted; Mansuria, Suketu

doi:10.1016/j.jmig.2013.03.012

Cited by 40 publications

(37 citation statements)

References 19 publications

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“…18 Arden D et al have compared instillation of 100 mg bupivacaine in 100 ml normal saline with instillation of 100 ml normal saline alone and concluded that bupivacaine was effective in reducing postoperative pain. 19 Ranjita et al in his study concluded that better postoperative analgesia can be provided with intraperitoneal, ropivacaine with dexamedetomidine after laparoscopic hysterectomy compared to ropivacaine alone. 20 These results agree with the current study.…”

Section: 12mentioning

confidence: 98%

Intraperitoneal analgesia for postoperative pain relief after laparoscopic gynecological surgeries

Pati¹

2017

Int J Reprod Contracept Obstet Gynecol

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Background: Though laparoscopic gynaecological surgeries are less invasive and produces less post-operative pain, post-laparoscopy pain is still a concern. Intraperitoneal (IP) instillation of local anaesthetics has been shown to minimize the postoperative pain after laparoscopic surgeries. This study was conducted to compare the efficacy of intraperitoneal instillation of dexmedetomidine with bupivacaine and bupivacaine alone in reducing postoperative pain.Methods: 60 patients, enrolled for gynaecological laparoscopic surgeries were divided randomly into two groups of 30 each. Group B: Bupivacaine (30 ml, 0.25%) with 2 ml normal saline was instilled prior to removal of trocars, and Group BD: Bupivacaine (30 ml, 0.25%) with dexmedetomidine (1 mcg/kg, diluted to 2 ml) was instilled prior to removal of trocars. In postoperative period, Visual Analogue Score (VAS) was recorded up to 24 hours. Postoperative analgesic requirements, and side effects were recorded.Results: The Visual Analogue Score (VAS) during the first postoperative 24 hours was significantly lower in group BD compared to group B. Time to first analgesia required was delayed and total analgesic consumption was lower in group BD compared to group B which was statistically significant.Conclusions: Intraperitoneal instillation of dexmedetomidine with bupivacaine is an effective and safe method for reducing pain after laparoscopic gynaecological surgeries.

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Section: 12mentioning

confidence: 98%

Intraperitoneal analgesia for postoperative pain relief after laparoscopic gynecological surgeries

Pati¹

2017

Int J Reprod Contracept Obstet Gynecol

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“…The first compared instillation of 100 mg bupivacaine in 100 mL normal saline with instillation of 100 mL normal saline [27]. The second compared a 48-hour infusion of 100 mL of .5% levobupivacaine to an infusion of 100 mL normal saline [28].…”

Section: Discussionmentioning

confidence: 99%

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

Rivard¹,

Teoh²

2014

Gynecologic Oncology

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“…[18] Arden D et al have compared instillation of 100 mg bupivacaine in 100 mL normal saline with instillation of 100 mL normal saline alone and concluded that bupivacaine was effective in reducing postoperative pain. [19] Ranjita et al in his study concluded that better postoperative analgesia can be provided with intraperitoneal, ropivacaine with dexamedetomidine after total laparoscopic hysterectomy compared to ropivacaine alone. [20] These results agree with the current study.…”

Section: Section: Surgerymentioning

confidence: 99%

Intraperitoneal Analgesia for Postoperative Pain Relief after Laparoscopic Surgeries

Sethy¹

2017

AIMDR

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Background: Though laparoscopic surgeries is less invasive and produces less post-operative pain,post-laparoscopy pain is still a concern. Intraperitoneal (IP) instillation of local anaesthetics has been shown to minimize the postoperative pain after laparoscopic surgeries. This study was conducted to compare the efficacy of intraperitoneal instillation of dexmedetomidine with bupivcaine and bupivacaine alone in reducing postoperative pain. Methods: 60 patients, enrolled for laparoscopic surgeries were divided randomly into two groups of 30 each. Group B: Bupivacaine (30ml,0.25%) with 2 ml normal saline was instilled prior to removal of trocars, and Group BD: Bupivacaine(30ml,0.25%) with dexmedetomidine(1mcg/kg,diluted to 2 ml) was instilled under prior to removal of trocars . In postoperative period, Visual Analogue Score (VAS) was recorded up to 24 hours. Postoperative analgesic requirements, and side effects were recorded. Results: The Visual Analogue Score (VAS) during the first postoperative 24 hours was significantly lower in group BD compared to group B. Time to first of analgesia required was delayed and total analgesic consumption was lower in group BD compared to group B which was statistically significant. Conclusion: Intraperitoneal instillation of dexmedetomidine with bupivcaine is an effective and safe method for reducing pain after laparoscopic surgeries.

show abstract

Intraperitoneal Instillation of Bupivacaine for Reduction of Postoperative Pain After Laparoscopic Hysterectomy: A Double-Blind Randomized Controlled Trial

Cited by 40 publications

References 19 publications

Intraperitoneal analgesia for postoperative pain relief after laparoscopic gynecological surgeries

Intraperitoneal analgesia for postoperative pain relief after laparoscopic gynecological surgeries

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

Intraperitoneal Analgesia for Postoperative Pain Relief after Laparoscopic Surgeries

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