2016
DOI: 10.1002/lt.24390
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Intrapulmonary vascular dilatations are common in portopulmonary hypertension and may be associated with decreased survival

Abstract: We read with interest the recently published article by Fussner et al. (1) in Liver Transplantation. The authors showed that intrapulmonary vascular dilatations (IPVDs), detected by agitated saline contrast-enhanced transthoracic echocardiography (cTTE), were common in patients with portopulmonary hypertension (POPH)-59% of patients. Moreover, this finding was associated with decreased survival, and the authors suggest the possibility of a pathophysiological overlap between POPH and hepatopulmonary syndrome in… Show more

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Cited by 2 publications
(2 citation statements)
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“…POPH is identified by an increase in pulmonary arterial pressure and a bloodstream flow impediment secondary to progressive obstruction of the arterial vascular bed 7 , leading to a step-by-step dysfunction of the right-sided heart. POPH criteria were described in 2004 by the Task Force on pulmonary-hepatic disorders and were maintained in the International Liver Transplant Society practice guidelines for the hepatopulmonary syndrome and POPH [8][9][10] (Table 1).…”
Section: Definitionmentioning
confidence: 99%
See 1 more Smart Citation
“…POPH is identified by an increase in pulmonary arterial pressure and a bloodstream flow impediment secondary to progressive obstruction of the arterial vascular bed 7 , leading to a step-by-step dysfunction of the right-sided heart. POPH criteria were described in 2004 by the Task Force on pulmonary-hepatic disorders and were maintained in the International Liver Transplant Society practice guidelines for the hepatopulmonary syndrome and POPH [8][9][10] (Table 1).…”
Section: Definitionmentioning
confidence: 99%
“…Intrapulmonary vascular dilations (IPVDs) have been reported in up to 59% of patients, suggesting an overlap between POPH and the hepatopulmonary syndrome. Their presence can compromise treatment (induce hypoxemia) as well as outcome/survival, especially in the LT setting 7 .…”
Section: Diagnosismentioning
confidence: 99%