Intrarenal Doppler: characteristics of aging kidneys

Terry, J D; Rysavy, J A; Frick, Mathis P.

doi:10.7863/jum.1992.11.12.647

Cited by 80 publications

(45 citation statements)

References 4 publications

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“…The intrarenal RI values in patients aged over 60 tend to be higher than those in younger adults (Rawashdeh et al, 2001;Terry et al, 1992). This may be ascribed to true renal dysfunction in senescent kidneys and that is not solely due to misleading variations or an age-dependent variability in the RI (Platt et al, 1994a).…”

Section: Children and The Elderlymentioning

confidence: 98%

The Evaluation of Renal Hemodynamics with Doppler Ultrasonography

Kaya¹

2012

Hemodynamics - New Diagnostic and Therapeutic Approaches

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Section: Children and The Elderlymentioning

confidence: 98%

The Evaluation of Renal Hemodynamics with Doppler Ultrasonography

Kaya¹

2012

Hemodynamics - New Diagnostic and Therapeutic Approaches

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“…Some groups have specifically studied the age dependency of RRI in adults. 4,5,11,14,15 Nevertheless, to our knowledge, only 2 smaller studies provided continuous baseline values for the healthy population according to age, 11,16 but subjects were not randomly selected and the studies were not population based. We also showed that the relationship of RRI with age is nonlinear and that RRI increases sharply after 40 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…In a population-based sample with normal renal ultrasound, RRI normal values depend on sex, age, blood pressure, heart rate, and body mass index. 4,5,[10][11][12][13][14][15][16] Most of them have described an increase of RRI with age and even suggested a value >0.7 as being pathological without establishing normal values according to age. One study from the 1990s found RRI to be associated with heart rate, 10 but other factors have not been systematically explored in a population-based sample.…”

mentioning

confidence: 99%

Reference Values and Factors Associated With Renal Resistive Index in a Family-Based Population Study

et al. 2014

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Renal Doppler was introduced in the 1980s to screen for renovascular disease and detect renal artery stenosis. 1It was also studied as a potential tool to improve the assessment of renal obstruction or transplant dysfunction. 2 The renal resistive index (RRI) obtained by the Doppler arterial waveform analysis is the most popular measure described in these pathologies. 3 It is a noninvasive and reproducible measure to investigate renal hemodynamics, 4 calculated from the peak systolic and end-diastolic velocities using the following equation: ([peak systolic velocity−end-diastolic velocity]/peak systolic velocity). RRI is based on the changes in flow velocity created by the pulsatile arterial perfusion and can be used as an estimate of renal arterial resistance. For instance, vasomotor stimuli such as sympathetic activation or fluid load can induce changes in the RRI that indirectly reflect changes in the renal vascular resistance.5 Drugs affecting arteriolar vasomotor properties, such as nitroglycerine or captopril, have also been reported to change RRI. 6,7 However, a preserved vascular compliance seems to be necessary for vascular resistance to affect RRI. 8 Hence, with increasing downstream resistance, the diastolic velocity falls relative to systolic value, and RRI increases. In contrast, in the presence of a significant (>70%) main artery stenosis, the diastolic blood flow is less affected, but a slower systole with a dampened waveform (called parvus tardus) is observed, resulting in a decreased RRI value. 9 Even with the widespread use of RRI, reference values and systematic factors influencing measurement values are not well known. Only small-sized studies have evaluated Abstract-Increased renal resistive index (RRI) has been recently associated with target organ damage and cardiovascular or renal outcomes in patients with hypertension and diabetes mellitus. However, reference values in the general population and information on familial aggregation are largely lacking. We determined the distribution of RRI, associated factors, and heritability in a population-based study. Families of European ancestry were randomly selected in 3 Swiss cities. Anthropometric parameters and cardiovascular risk factors were assessed. A renal Doppler ultrasound was performed, and RRI was measured in 3 segmental arteries of both kidneys. We used multilevel linear regression analysis to explore the factors associated with RRI, adjusting for center and family relationships. Sex-specific reference values for RRI were generated according to age. Heritability was estimated by variance components using the ASSOC program (SAGE software). Four hundred women (mean age±SD, 44.9±16.7 years) and 326 men (42.1±16.8 years) with normal renal ultrasound had mean RRI of 0.64±0.05 and 0.62±0.05, respectively (P<0.001). In multivariable analyses, RRI was positively associated with female sex, age, systolic blood pressure, and body mass index. We observed an inverse correlation with diastolic blood pressure and heart rate. Age had a nonli...

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“…This is one of the major limita- (Terry et al 1992;Rivers et al 1997). In the present study, one of the dogs with increased RI and PI was seventeen years old.…”

Section: Discussionmentioning

confidence: 57%

Evaluation of early renal disease in bitches with pyometra based on renal doppler measurements

Koenhemsi¹,

Toydemir²,

Uçmak³

et al. 2016

Vet. Med. - Czech

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Pyometra is a widely detected, chronic infection of the uterus. One of the complications of this infection is renal disease. Kidney biopsy, urinary biomarkers and blood tests were done to detect pyometra-associated renal disease. To our knowledge, no reports are available describing values for renal Doppler measurements in the bitches with pyometra. Doppler ultrasonography is a relatively new method used for evaluation of the renal diseases. The aims of this study were to determine whether renal vascular resistance does increase in dogs with pyometra and to make an early diagnosis of renal disease in dogs with pyometra. Eighteen bitches diagnosed with pyometra and ten healthy bitches were evaluated. Mean values for renal resistive index (RI) and pulsatility index (PI) were 0.65 ± 0.02 and 1.73 ± 0.09 for dogs with pyometra; 0.55 ± 0.03 and 1.18 ± 0.03 for the healthy ones, respectively. Of these, four animals had increased RI values and fourteen had an increased PI level. In conclusion, renal vascular resistance determined by renal RI and PI, was increased in some dogs with pyometra. In early detection of the disease intrarenal PI values were more sensitive than intrarenal RI.

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Intrarenal Doppler: characteristics of aging kidneys

Cited by 80 publications

References 4 publications

The Evaluation of Renal Hemodynamics with Doppler Ultrasonography

The Evaluation of Renal Hemodynamics with Doppler Ultrasonography

Reference Values and Factors Associated With Renal Resistive Index in a Family-Based Population Study

Evaluation of early renal disease in bitches with pyometra based on renal doppler measurements

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