Intrarenal mature cystic teratoma associated with renal dysplasia: Case report and literature review

Abstract

We report a case of intrarenal teratoma in a 6-year-old boy. Two years before his operation, multicystic masses had been found in the left side of his abdomen. In the operation, three main cystic masses were located in the upper and lower poles of the left kidney, which were removed in pieces. Histologically, the cyst wall was lined mainly with keratinizing squamous epithelium with hair follicles, shafts and sebaceous glands. The adjacent renal parenchyma showed atrophy, with partially dysplastic and angiomyolipoma-like lesions. Based on these findings, the lesion was diagnosed as mature cystic teratoma of dermoid cyst type. Extragonadal teratoma occurs predominantly along the median line of the body. Intrarenal teratoma is extremely rare; however, it should be distinguished from teratoid Wilms' tumor and other renal cystic lesions.

Primary Intra-Renal Teratoma Associated with Renal Dysplasia: An Unusual Entity

“…Primary intrarenal teratoma is an exceeding rarity with less than 30 cases reported [1][2][3][4][5]. The patients' age ranged from 6 weeks to 71 years; a little more than half of these teratomas arose in children [1,2].…”

“…The patients' age ranged from 6 weeks to 71 years; a little more than half of these teratomas arose in children [1,2]. The chief presenting symptoms included abdominal mass, abdominal pain, anorexia, vomiting, constipation and haematuria.…”

“…Renal teratomas include both mature and immature types. Only two cases of renal teratoma in association with renal dysplasia have been published in literature [2,5]. Renal teratomas associated with carcinoid tumour have also been reported.…”

“…Associated congenital anomalies such as horseshoe-kidney, duplicated collecting system, etc. are occasionally seen [1,2].…”

“…A review of literature since 1915 shows less than 30 reports of primary intrarenal teratomas [1][2][3][4][5]. Intrarenal teratoma associated with renal dysplasia is an even rarer occurrence, with only two reported cases on record [2,5].…”