Intrasession Test–Retest Variability of Microperimetry in Age-Related Macular Degeneration

Wu, Zhichao; Ayton, Lauren N; Guymer, Robyn H.; Luu, Chi D

doi:10.1167/iovs.13-12617

Cited by 114 publications

(147 citation statements)

References 28 publications

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“…24 We had expected that given the short duration of each test, participants would have required a greater number of examinations before becoming familiarized with this test and, thus, exhibit a learning effect over several examinations. Instead, we did not find a significant intrasession learning effect and, therefore, these measurements could be used to compare to those obtained by microperimetry.…”

Section: Discussionmentioning

confidence: 99%

“…24 In short, the MAIA microperimeter performs fundus-tracking using a line scanning laser ophthalmoscope that illuminates the fundus using a superluminescent diode with a central wavelength of 850 nm, using the entire fundus as a reference for fundus tracking at 25 frames per second. A red circle 18 in diameter was used as a fixation target, and Goldman III sized stimuli were presented against a background of 1.27 cd/m 2 using a 4-2 staircase threshold strategy.…”

Section: Microperimetric Examinationmentioning

confidence: 99%

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Measurement of Retinal Sensitivity on Tablet Devices in Age-Related Macular Degeneration

Guymer

Jung

et al. 2015

Trans. Vis. Sci. Tech.

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Purpose: We compared measurements of central retinal sensitivity on a portable, lowcost tablet device to the established method of microperimetry in age-related macular degeneration (AMD).Methods: A customized test designed to measure central retinal sensitivity (within the central 18 radius) on a tablet device was developed using an open-source platform called PsyPad. A total of 30 participants with AMD were included in this study, and all participants performed a practice test on PsyPad, followed by four tests of one eye and one test of the other eye. Participants then underwent standardized microperimetry examinations in both eyes. Results:The average test duration on PsyPad was 53.9 6 7.5 seconds, and no significant learning effect was observed over the examinations performed (P ¼ 1.000). The coefficient of repeatability of central retinal sensitivity between the first two examinations on PsyPad was 61.76 dB. The mean central retinal sensitivity was not significantly different between PsyPad (25.7 6 0.4 dB) and microperimetry (26.1 6 0.4 dB, P ¼ 0.094), and the 95% limits of agreement between the two measures were between À4.12 and 4.92 dB. Conclusions:The measurements of central retinal sensitivity can be performed effectively using a tablet device, displaying reasonably good agreement with those obtained using the established method of microperimetry.Translational Relevance: These findings highlight the potential of tablet devices as low-cost and portable tools for developing and performing visual function measures that can be easily and widely implemented.

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Section: Discussionmentioning

confidence: 99%

Section: Microperimetric Examinationmentioning

confidence: 99%

Measurement of Retinal Sensitivity on Tablet Devices in Age-Related Macular Degeneration

Guymer

Jung

et al. 2015

Trans. Vis. Sci. Tech.

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“…As shown in earlier studies, automatic fundus perimetry and the first microperimetry that uses a true eye-tracking system (MP1) allow accurate, repeatable, and topographically specific examination of retinal sensitivity [4,[7][8][9][10][11][12].…”

Section: Discussionmentioning

confidence: 98%

“…These results strongly suggest that there is no learning effect of retinal average sensitivity and macular integrity by using MAIA microperimetry. In the literature, Wu et al [11] showed a significant learning effect on mean sensitivity between the first and the second test sections in AMD patients with MP1 microperimetry. In contrast, Wong et al [15] demonstrated no learning effect on the mean sensitivity in glaucoma patients by using MAIA microperimetry.…”

Section: Discussionmentioning

confidence: 99%

Retinal Sensitivity and Fixation Stability Changes during Repeated Microperimetry

Szepessy¹,

Barboni²,

Nagy³

et al. 2017

J Clin Exp Ophthalmol

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Purpose: To determine and compare the intersession test-retest variability of different microperimetric parameters in healthy volunteers and age-related macular degeneration (AMD) patients by MAIA microperimetry.Methods: Twenty-four eyes of 12 healthy volunteers and 22 eyes of 11 AMD patients were included in this study. Microperimetry examinations were performed three times on each eye of all participants by MAIA microperimetry (CenterVue, Padova, Italy). The second measurement was performed on the same day and the third measurement one week after the first test. Retinal light sensitivity, stability of fixation, and macular integrity were recorded. Statistical analysis was performed by Microsoft Excel software and StatSoft Statistica software.Results: During the examinations, the average threshold had not changed significantly (p>0.475) in time in healthy and AMD patients. Fixation stability was relatively constant (nearly 100%) in healthy subjects as compared to the increase in the improving eye condition of AMD patients (p=0.042). Macular integrity was stable in both groups during the examinations. Conclusion:A learning effect was found in fixation stability of AMD patients by MAIA microperimetry. The improvement in fixation stability might be considered, especially prior to biofeedback training protocols in AMD patients.

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“…Test durations for both standard and reduced mesopic conditions were approximately 10 minutes after a practise test was completed to avoid the influence of a learning effect (Wu, Ayton, Guymer & Luu 2013). …”

Section: Microperimetrymentioning

confidence: 99%

Image and Non-Image Forming Melanopsin Function in Age-Related Macular Degeneration

Maynard¹

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Intrasession Test–Retest Variability of Microperimetry in Age-Related Macular Degeneration

Cited by 114 publications

References 28 publications

Measurement of Retinal Sensitivity on Tablet Devices in Age-Related Macular Degeneration

Measurement of Retinal Sensitivity on Tablet Devices in Age-Related Macular Degeneration

Retinal Sensitivity and Fixation Stability Changes during Repeated Microperimetry

Image and Non-Image Forming Melanopsin Function in Age-Related Macular Degeneration

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