Intrathoracic Tracheal Tumors: Development of Surgical Technics for Their Removal

Clagett, O. Theron; Moersch, Herman J.; Grindlay, John H.

doi:10.1097/00000658-195209000-00017

Cited by 26 publications

(19 citation statements)

References 5 publications

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“…Adenoid cystic carcinoma (ACC) or ''cylindroma'' is a malignant tumour with slow growth, however paratracheal extension and invasion of adjacent structures is common. Surgery is indicated once diagnosis has been made [2].…”

Section: Discussionmentioning

confidence: 99%

Peripheral Cardiopulmonary Bypass under Local Anaesthesia for Tracheal Tumour Resection

Villanueva

Milder

Manganas

2015

Heart, Lung and Circulation

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Section: Discussionmentioning

confidence: 99%

Peripheral Cardiopulmonary Bypass under Local Anaesthesia for Tracheal Tumour Resection

Villanueva

Milder

Manganas

2015

Heart, Lung and Circulation

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“…Tracheal replacement using prostheses was also investigated under clinical conditions using stainless steel [10] , steel coil [11] , silicone [12,13] , polyethylene [14,15] , and Tefl on [16] . Neville silicone prostheses have probably been the most accepted tracheal substitute but are hampered by the lack of epithelization with recurrent suture line granulomas and subsequent stenosis, the tendency to dislodgement and 5.…”

Section: Discussionmentioning

confidence: 99%

Repair of Non-Circumferential Cervical Trachea Defects by Three Different Latissimus Dorsi Flaps

Christoforidis

Pezzetta²,

Simon-Valla³

et al. 2005

Eur Surg Res

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Background: Large intrathoracic airway defects may be closed using a pedicled latissimus dorsi (LD) flap, with rewarding results. This study addresses the question of whether this holds true for extrathoracic non-circumferential tracheal defects. Methods: A cervical segment of the trachea of 4 × 1 cm was resected in 9 white male pigs. The defect was stented with a silicone stent for 3 months and closed either by an LD flap alone (group a, n = 3), an LD flap with an attached rib segment covered by pleura (group b, n = 3), or an LD flap reinforced by a perforated polylactide (MacroPore^®) plate (group c, n = 3). The trachea was assessed by rigid endoscopy at 3 and 4 months and histologically at 4 months postoperatively. Results: The degree of stenosis at the level of the reconstruction at 4 months was 25, 50 and 75% in group a, 15, 50 and 60% in group b, and 20, 95 and 95% in group c, respectively. The percentage of the defect covered by columnar epithelium was 100% in all animals of group a, 60, 100 and 100% in group b, and 10, 0 and 0% in group c. Resorption of the rib was seen in all animals of group b and obstructive inflammatory polyps were found in 2 animals of group c. Conclusion: Pedicled LD flaps provided less satisfactory results for closure of large non-circumferential extrathoracic airway defects than observed after intrathoracic reconstruction. A pedicled rib segment added to the LD flap did not improve the results obtained from LD flap repair alone, and an embedded MacroPore^® prosthesis may result in severe airway stenosis due to plate migration and intense inflammatory reaction protruding into the tracheal lumen.

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“…For all of these attempts, it was found that autogenous patches generally results in fibrotic contraction with patchy epithelization. Clinically, steel coil supported fascia has been employed in malignant tumors resections [26]. Larger dermal grafts for tracheal repair were mostly unsuccessful [51,76], but limited patch reconstructions were moderately successful [77,78].…”

Section: Autograft Transplantationmentioning

confidence: 99%

Tracheal Tissue Engineering

Birla

2014

Introduction to Tissue Engineering

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Intrathoracic Tracheal Tumors: Development of Surgical Technics for Their Removal

Cited by 26 publications

References 5 publications

Peripheral Cardiopulmonary Bypass under Local Anaesthesia for Tracheal Tumour Resection

Peripheral Cardiopulmonary Bypass under Local Anaesthesia for Tracheal Tumour Resection

Repair of Non-Circumferential Cervical Trachea Defects by Three Different Latissimus Dorsi Flaps

Tracheal Tissue Engineering

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