Intrathyroidal Parathyroid Adenoma Or Hyperplasia

Spiegel, Allen M.; Marx, Stephen J.; Doppman, John L.; Beazley, Robert M.; Ketcham, Alfred S.; Kasten, B; Aurbach, G. D.

doi:10.1001/jama.1975.03260230029018

Cited by 24 publications

(1 citation statement)

References 10 publications

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“…Blunt dissection behind the manubrium of the sternum and exposure of the thymus often allows the excision of mediastinal tumors. The possibility of intrathyroidal parathyroids must also be considered, since they are present in 8% of the cases [25]. A hemithyroidectomy on the side of the missing parathyroid gland is sometimes indicated.…”

Section: The Surgical Strategymentioning

confidence: 99%

Surgical treatment of hyperparathyroidism

Egdahl

1977

World j. surg.

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A dramatic rise in the number of diagnosed cases of hyperparathyroidism has been accompanied by significant progress in diagnostic and management techniques. Indications for parathyroid surgical exploration have been established for cases presenting with hypercalcemia and any of several clinical syndromes. Asymptomatic or mildly symptomatic patients with the disease can be followed for longer intervals prior to surgery, but surgical treatment is recommended. Normocalcemic hyperparathyroidism with repeated renal stones exists as a disease entity and further investigation is needed to determine guidelines for operative treatment. Surgery is reserved for medically intractable cases in secondary hyperparathyroidism. The surgical strategy should be based on the identification of all glands and, with few exceptions, only abnormal tissue should be resected. Mediastinal explorations are rarely needed and should always be preceded by careful localization studies. Surgical results are generally good, with low recurrence rates if definitive surgery is possible. Mortality and morbidity rates are also very low and, while the most common postoperative complication is temporary hypocalcemia, vocal cord paralysis is a rare but debilitating one.

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Section: The Surgical Strategymentioning

confidence: 99%

Surgical treatment of hyperparathyroidism

Egdahl

1977

World j. surg.

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Parathyroid Anatomy in Hyperplasia

Liechty

Weil²

1992

Arch Surg

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Pathologically enlarged parathyroid glands offer the surgeon a vital medium for studying parathyroid anatomy. The advantages include gland magnification, rapid-section diagnosis to aid dissections, and postoperative clinical and laboratory responses to check for "missed" or supernumerary glands. In this series, each of 71 patients had at least four hyperplastic glands. Both mediastinal and intrathyroidal glands occurred in nine instances (13%), supernumerary glands in eight (11%), and ectopic neck glands in seven (10%). In total, anomalous parathyroid glands occurred in almost half (46%) of these patients with parathyroid hyperplasia.

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Causes of failure in the surgical treatment of primary hyperparathyroidism: Lessons from 51 successful reoperations

Vroonhoven

Müller

1978

Journal of British Surgery

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A review of 51 successful reoperations for persisting hypercalcaemia due to primary hyperparathyroidism shows that inadequate anatomical knowledge, inadequate surgical technique and unusual localizations of the parathyroids are the most frequent causes of failure of the primary operation. The majority of these failures are therefore preventable. There is a frequent need for cervical thymectomy in parathyroid surgery. Sternotomy is only very rarely necessary.

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Intrathyroidal Parathyroid Adenoma Or Hyperplasia

Cited by 24 publications

References 10 publications

Surgical treatment of hyperparathyroidism

Surgical treatment of hyperparathyroidism

Parathyroid Anatomy in Hyperplasia

Causes of failure in the surgical treatment of primary hyperparathyroidism: Lessons from 51 successful reoperations

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