Intrathyroidal parathyroid adenoma presenting with neuromuscular manifestation

Abstract

Primary hyperparathyroidism (PHPT) is not an uncommon endocrine disorder. We describe a patient with PHPT who presented with progressive proximal limbs weakness and dystrophic changes of leg muscles. Serum calcium, alkaline phosphatase, and parathyroid hormone were elevated and serum phosphorus was low. Neck computerized tomography scan showed a parenchymatous tumor in the right lobe of the thyroid. The tumor presented as a 'cold nodule' in the dual-phase single-agent Tc-99m MIBI scan. The right lobectomy examination confirmed the diagnosis of an intrathyroidal parathyroid adenoma of the right gland.

Hypokalemic periodic paralysis: an unusual presentation of primary hyperparathyroidism

“…9,10,11 There is one anecdotal report of intrathyroid parathyroid adenoma presenting with neuromuscular manifestation. 12 But to our knowledge, there are no reports of an oncocytic variant of intrathyroidal parathyroid adenoma presenting with hypokalemic periodic paralysis in the literature till date and this is the first case to be reported with such an unusual presentation.…”

Intrathyroidal Parathyroid Adenoma: A Case Report and Review of The Literature

“…İntratiroidal paratiroid adenomu nadir görülen bir durumdur 5 . Ektopik paratiroid dokusu embriyolojik göç yoluna bağlı olarak sıklıkla üçüncü veya dördüncü faringeal poş ile ilişkili yapılarda ortaya çıkmaktadır.…”

The Prognostic Value of The Platelet/Lymphocyte Ratio in Predicting Short-Term Mortality in Patients with Acute Pulmonary Embolism

“…Brain natriuretic peptide (BNP) and N-terminal brain natriuretic peptide (NT-proBNP) that can suggest right ventricular dysfunction are also used for prognosis 5 . Recent guidelines demonstrated that the simplified pulmonary embolism severity index (sPESI) score could be useful for the prediction of prognosis and mortality in patients with acute PE 6 .…”