“…As an example, the danger of heat extremes for public health was particularly evident in August 2003 in Western Europe, when the heat wave had caused over 70,000 additional deaths [1,27,28,47,68,83,119]. In 2010, a "mega heatwave" with maximum temperatures up to 40°C and the combined effect of heat and smoke from numerous wildfires, covered Eastern Europe, the European part of Russia and southern Siberia [47]; estimates for the death toll were 55,000 in Russia and 11,000 in Moscow, with 15 billion USD of total economic loss, which was near 1% Russian gross domestic product [5,10,20,21,23,24,28,35,42,47,51,61,93,108,114,128,138]. According to World Health Organization, in the European region (43 countries) in the period from 2071 to 2099, heat waves could lead to 47-117,000 additional deaths annually [77].…”