Intrauterine insemination (IUI) pregnancy outcome is enhanced by shorter intervals from semen collection to sperm wash, from sperm wash to IUI time, and from semen collection to IUI time

The effect of intrauterine insemination time on semen parameters

“…Semen washed within 30 minutes after collection resulted in a higher pregnancy rate than that processed 31-60 minutes after collection in hMG-treated but not in CC-treated women. IUI performed within 90 minutes after collection resulted in a higher pregnancy rate than IUI performed at 91-120 minutes or >120 minutes after collection in hMGtreated but not in CC-treated women (8).…”

The Effect of Intervals from Sperm Wash to Intra Uterine Insemination (IUI) Time on Pregnancy Rate

“…In our literature review, in a single retrospective study conducted with 102 patients to determine the effect of the interval between sperm wash and IUI on pregnancy rates, it was reported that there was no difference between performing IUI in intervals of 30 minutes and 31-60 minutes, but pregnancy rates were higher in these two groups compared to the group in which IUI was administered after 60 minutes, and that no pregnancy was observed in the group in which hMG was used after 180 minutes (11) . In this study, in the groups with 30 minutes, 31-60 minutes, >60 minutes interval, pregnancy rates were 6%, 6% and 15%, respectively, in the CC group; and 67%, 42% and 7%, respectively, in the hMG group.…”

“…Several factors, such as maternal age, cause of infertility, uterine factor, sperm parameters, presence of endometriosis, number of cycles and ovulation induction agents, have been investigated as prognostic factors for IUI success (3)(4)(5)(6)(7) . However, there is limited number of studies on the effect of other parameters that may affect pregnancy rates with IUI, such as the effect of the place of semen collection (house, clinic), intervals from semen collection to sperm wash and intervals from sperm wash to IUI on the IUI outcomes (8)(9)(10)(11) . In a retrospective study, it was reported that semen collection at home rather than in the clinic, increasing the interval between semen collection and sperm wash from 30 minutes to 60 minutes, and increasing the interval between sperm wash and IUI from 90 minutes to 120 minutes resulted in a significant decrease in pregnancy rate in hMG-IUI cycles (11) .…”

“…However, there is limited number of studies on the effect of other parameters that may affect pregnancy rates with IUI, such as the effect of the place of semen collection (house, clinic), intervals from semen collection to sperm wash and intervals from sperm wash to IUI on the IUI outcomes (8)(9)(10)(11) . In a retrospective study, it was reported that semen collection at home rather than in the clinic, increasing the interval between semen collection and sperm wash from 30 minutes to 60 minutes, and increasing the interval between sperm wash and IUI from 90 minutes to 120 minutes resulted in a significant decrease in pregnancy rate in hMG-IUI cycles (11) . On the other hand, it was found in another study that semen collection at home and delayed transport period did not have any effect on pregnancy rate (10) .…”

Intrauterine Insemination: Fundamentals Revisited

“…Delaying semen processing from 30 min up to 1 h and/or delaying IUI from 90 min up to 2 h after collection compromises the pregnancy outcome in gonadotropin-IUI cycles [1]. A universal threshold level above which IUI can be performed with acceptable pregnancy rates has not been determined yet [2].…”