Intrauterine Levobupivacaine Instillation for Pain Control in Women Undergoing Diagnostic Hysteroscopy

Abdelazim, IbrahimA; El-Ghazaly, TamerE; Elshabrawy, A

doi:10.4103/gmit.gmit_48_21

Cited by 7 publications

(7 citation statements)

References 16 publications

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“…Administration of analgesics may reduce this pain. [ 17 ] Using a gentle technique and avoiding holding the cervix with a tenaculum may also reduce this pain. [ 14 ]…”

Section: Discussionmentioning

confidence: 99%

Comparison of Efficacy of Vaginal Misoprostol versus a Synthetic Osmotic Dilator (Dilapan-S) for Cervical Preparation before Operative Hysteroscopy: A Randomized Controlled Study

Nair,

Subbaiah,

Maurya

2023

Gynecology and Minimally Invasive Therapy

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Objectives: To compare the need for mechanical cervical dilatation following vaginal misoprostol or synthetic osmotic dilator (Dilapan-S) usage for cervical preparation before operative hysteroscopy. Materials and Methods: Fifty-five premenopausal women scheduled for operative hysteroscopic procedures with a 26 Fr resectoscope were included in this randomized, controlled clinical trial. After randomization, either 400 μg of vaginal misoprostol or intracervical synthetic osmotic dilator (Dilapan-S) was inserted 12 h before operative hysteroscopy. The need for additional mechanical cervical dilatation before insertion of the resectoscope was compared between the two groups. Initial cervical diameter before mechanical dilatation, intraoperative complications (cervical tears, creation of a false passage), and ease of dilatation were also compared between the two groups. Results: In the misoprostol group, 92% of women required additional mechanical cervical dilatation, whereas only 36% of women in the Dilapan-S group required additional dilatation (P < 0.05). The median initial cervical diameter achieved with Dilapan was 9 mm (Q1: 7 mm; Q3: 10 mm), and with misoprostol, it was 6 mm (Q1: 4.5 mm; Q3: 8 mm) (P < 0.05). There was no significant difference in other outcome parameters between the two groups. Conclusion: Synthetic osmotic dilator (Dilapan-S) is more efficacious than vaginal misoprostol at ripening the cervix before operative hysteroscopy.

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“…Administration of analgesics may reduce this pain. [ 17 ] Using a gentle technique and avoiding holding the cervix with a tenaculum may also reduce this pain. [ 14 ]…”

Section: Discussionmentioning

confidence: 99%

Comparison of Efficacy of Vaginal Misoprostol versus a Synthetic Osmotic Dilator (Dilapan-S) for Cervical Preparation before Operative Hysteroscopy: A Randomized Controlled Study

Nair,

Subbaiah,

Maurya

2023

Gynecology and Minimally Invasive Therapy

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“…G Power 3.1.9.7 with 0.05 probability, 0.95% power, and 0.5 sample size was used to calculate the sample size [ 18 , 19 ].…”

Section: Methodsmentioning

confidence: 99%

The relationship between vitamin D and adolescents’ parathyroid hormone and bone mineral density

Donayeva,

Amanzholkyzy,

A. Abdelazim

et al. 2024

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Introduction To detect the relationship between 25-hydroxy vitamin D (25(OH)D) and adolescents’ parathyroid hormone (PTH) and bone mineral density (BMD). Material and methods Two hundred adolescent girls were recruited for this cross-sectional comparative study. After detailed evaluation, a pelvic sonography was performed for the studied adolescents to rule out any pelvic pathology. Adolescents’ blood samples were collected to measure the thyroid stimulating hormone, prolactin, glycosylated haemoglobin (HbA 1C ), PTH, and 25(OH)D. The studied adolescents’ BMD and the T-score were evaluated at 2 anatomical sites. The studied adolescents were classified according to their serum 25(OH)D into 2 groups: a 25(OH)D-deficient group (study group; 25(OH)D < 20 ng/ml) and normal controls (25(OH)D > 30 ng/ml). Student’s t-test was used for analysis of the studied adolescents’ variables, and correlation analysis (Pearson`s correlation) was used to detect the relationship between 25(OH)D and adolescents’ PTH and BMD. Results The parathyroid hormone was statistically higher in the 25(OH)D-deficient group than in the normal controls (41.3 ±3.4 pg/ml vs. 21.1 ±2.8) ( p = 0.02), and the BMD was statistically lower in the 25(OH)D-deficient group than in the normal controls (–1.25 ±0.5 vs. 0.3 ±0.4) ( p = 0.01). The 25(OH)D had a significant negative correlation with the adolescents’ PTH ( r = –0.9175; p < 0.00001) and a significant positive correlation with the adolescents’ BMD ( r = 0.756; p < 0.00001). The parathyroid hormone had a significant negative correlation with the adolescents’ BMD ( r = –0.7006; p < 0.00001). Conclusions The parathyroid hormone in this study had significant negative correlations with both 25(OH)D and BMD. The 25(OH)D had a significant positive correlation with the studied adolescents’ BMD.

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“…The severity of the studied adolescents’ dysmenorrhea was assessed by the VAS [ 13 ]. The visual analogue scale score of 0 equals no menstrual pain and/or dysmenorrhea.…”

Section: Methodsmentioning

confidence: 99%

The relation between primary dysmenorrhea in adolescents and body mass index

Donayeva,

Amanzholkyzy,

Nurgaliyeva

et al. 2023

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Introduction The aim was to assess the relation between primary dysmenorrhea in adolescents and body mass index (BMI). Material and methods Two-hundred and ten adolescents were recruited for this cross-sectional research. After detailed evaluation, pelvic sonography was performed for the studied adolescents to rule out any pelvic abnormalities and/or lesion(s). The severity of the studied adolescents’ dysmenorrhea was assessed by the visual analogue scale (VAS). The studied adolescents were divided into underweight, normal-weight, overweight, and obese adolescent groups based on their BMI (kg/m 2 ). Collected data were analyzed using the ANOVA test, and correlation analysis (Pearson’s correlation) to assess the relation between primary dysmenorrhea in adolescents and BMI. Results The visual analogue scale of dysmenorrhea was statistically higher in the underweight adolescent group (8.7 ±0.8) compared to normal-weight (6.5 ±0.5) ( p = 0.000001), and overweight (6.3 ±0.6) ( p = 0.000001) adolescent groups. The visual analogue scale of dysmenorrhea was also statistically higher in the obese adolescent group (9.4 ±0.6) compared to underweight (8.7 ±0.8) ( p = 0.000001), normal-weight (6.5 ±0.5) ( p = 0.000001), and overweight (6.3 ±0.6) ( p = 0.000001) adolescent groups. Conclusions The visual analogue scale of dysmenorrhea was statistically higher in the underweight adolescent group compared to normal-weight, and overweight adolescent groups, and there was a strong negative relation between the VAS and BMI in the underweight adolescent group. In addition, the VAS of dysmenorrhea was statistically higher when the obese adolescent group was compared with the overweight, normal-weight and underweight adolescent groups, and there was a moderate positive relation between the VAS and BMI in the obese adolescent group.

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Intrauterine Levobupivacaine Instillation for Pain Control in Women Undergoing Diagnostic Hysteroscopy

Cited by 7 publications

References 16 publications

Comparison of Efficacy of Vaginal Misoprostol versus a Synthetic Osmotic Dilator (Dilapan-S) for Cervical Preparation before Operative Hysteroscopy: A Randomized Controlled Study

Comparison of Efficacy of Vaginal Misoprostol versus a Synthetic Osmotic Dilator (Dilapan-S) for Cervical Preparation before Operative Hysteroscopy: A Randomized Controlled Study

The relationship between vitamin D and adolescents’ parathyroid hormone and bone mineral density

The relation between primary dysmenorrhea in adolescents and body mass index

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