Intrauterine photoacoustic and ultrasound imaging probe

Miranda, Christopher; Barkley, Joel; Smith, Barbara

doi:10.1117/1.jbo.23.4.046008

Cited by 16 publications

(9 citation statements)

References 55 publications

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“…Various research groups have implemented integrated PAT and US probes for clinical applications ( Levi et al, 2014 ; Dai et al, 2015 ; Kim et al, 2016 ; Miranda et al, 2018 ; Kothapalli et al, 2019 ; Zhang and Wang, 2020 ; Pang et al, 2022 ). A programmable US system can utilize various US transducers ( Figure 1 ) to generate PAT/US images ( Kim et al, 2016 ).…”

Section: Pat/us System For Clinical Translationmentioning

confidence: 99%

Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends

Wen

Guo²,

Zhang³

et al. 2022

Front. Physiol.

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Photoacoustic tomography (PAT) is an emerging biomedical imaging modality that combines optical and ultrasonic imaging, providing overlapping fields of view. This hybrid approach allows for a natural integration of PAT and ultrasound (US) imaging in a single platform. Due to the similarities in signal acquisition and processing, the combination of PAT and US imaging creates a new hybrid imaging for novel clinical applications. Over the recent years, particular attention is paid to the development of PAT/US dual-modal systems highlighting mutual benefits in clinical cases, with an aim of substantially improving the specificity and sensitivity for diagnosis of diseases. The demonstrated feasibility and accuracy in these efforts open an avenue of translating PAT/US imaging to practical clinical applications. In this review, the current PAT/US dual-modal imaging systems are discussed in detail, and their promising clinical applications are presented and compared systematically. Finally, this review describes the potential impacts of these combined systems in the coming future.

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Section: Pat/us System For Clinical Translationmentioning

confidence: 99%

Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends

Wen

Guo²,

Zhang³

et al. 2022

Front. Physiol.

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“…C, Example of a speckle pattern captured with the setup (128 × 16 pixel which enable the sampling of the speckle pattern at a field of view of 45 μm × 240 μm). The width is restricted by the fiber bundle diameter (240 μm), whereas the height (45 μm) is defined by the available pixel amount 16 For this work photoacoustic measurements in transmission mode and reflection mode, using the phantoms and the ex vivo sample, are carried out. For the phantom measurement, 15 single measurements per phantom are carried out and analyzed in order to ensure statistical relevance.…”

Section: Optical and Experimental Setupmentioning

confidence: 99%

“…Other groups combined the light delivery fiber and the transducer by placing them next to each other in one system . Furthermore, it is also possible to place the transducer on top of the optical fiber . Ji et al symmetrically placed two transducers next to the delivered light pulse .…”

Section: Introductionmentioning

confidence: 99%

Contact‐free endoscopic photoacoustic sensing using speckle analysis

Lengenfelder

Mehari

Hohmann

et al. 2019

Journal of Biophotonics

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Photoacoustic endoscopy (PAE) is an emerging imaging modality, which offers a high imaging penetration and a high optical contrast in soft tissue. Most of the developed endoscopic photoacoustic sensing systems use miniaturized contact ultrasound transducers or complex optical approaches. In this work, a new fiber‐based detection technique using speckle analysis for contact‐free signal detection is presented. Phantom and ex vivo experiments are performed in transmission and reflection mode for proof of concept. In summary, the potential of the technique for endoscopic photoacoustic signal detection is demonstrated. The new technique might help in future to broaden the applications of PAE in imaging or guiding minimally invasive laser procedures.

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“…Hence, to achieve this goal, photoacoustic endoscopy (PAE) has been developed over these years [ 5 ]. PAE has been employed as a valuable imaging modality in various applications, such as intravascular imaging [ 6 , 7 , 8 , 9 ], genitourinary imaging [ 10 , 11 , 12 , 13 ], esophageal [ 14 , 15 , 16 ], and gastrointestinal imaging [ 17 , 18 , 19 , 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field

et al. 2022

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This paper aims to propose a new photoacoustic/ultrasound endoscopic imaging reconstruction algorithm based on the approximate Gaussian acoustic field which significantly improves the resolution and signal-to-noise ratio (SNR) of the out-of-focus region. We demonstrated the method by numerical calculations and investigated the applicability of the algorithm in a chicken breast phantom. The validation was finally performed by the rabbit rectal endoscopy experiment. Simulation results show that the lateral resolution of the target point in the out-of-focus region can be well optimized with this new algorithm. Phantom experimental results show that the lateral resolution of the indocyanine green (ICG) tube in the photoacoustic image is reduced from 3.975 mm to 1.857 mm by using our new algorithm, which is a 52.3% improvement. Ultrasound images also show a significant improvement in lateral resolution. The results of the rabbit rectal endoscopy experiment prove that the algorithm we proposed is capable of providing higher-quality photoacoustic/ultrasound images. In conclusion, the algorithm enables fast acoustic resolution photoacoustic/ ultrasonic dynamic focusing and effectively improves the imaging quality of the system, which has significant guidance for the design of acoustic resolution photoacoustic/ultrasound endoscopy systems.

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Intrauterine photoacoustic and ultrasound imaging probe

Cited by 16 publications

References 55 publications

Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends

Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends

Contact‐free endoscopic photoacoustic sensing using speckle analysis

Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field

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