Lipomas are the most common soft tissue lesions in the subcutaneous area and when composed with collagenous tissue they are named fibrolipomas; which are a rare subtype of fat containing soft tissue tumors. They may ocur in any part of the body where the fat tissue is located. This slow growing benign lesion can be treated by total excision. We report a case of a 38-year old woman who had a giant mass on her back. Radiography evidenced a solid neoplasm measuring 25 cm in its major axis. A total excision was performed and the histology was consistent with fibrolipoma. We want to share our clinical experiences and discuss literature with this giant fibrolipoma case.