2017
DOI: 10.2169/internalmedicine.56.7804
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Intravascular Images of Coronary Stenosis with Multiple Channels in a Patient with Antiphospholipid Syndrome: The Optical Coherence Tomography Findings

Abstract: Intravascular images of coronary stenosis by antiphospholipid syndrome (APS) would be beneficial to understand the mechanism of this disease. A 59-year-old woman with APS/systemic lupus erythematosis (SLE) underwent emergent coronary angiography which revealed stenosis with micro channels in the proximal left anterior descending artery. According to optical coherence tomography (OCT), the central lumen was surrounded by a thick septum with a homogenous and high intensity. Multiple small channels existed near t… Show more

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Cited by 7 publications
(5 citation statements)
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“…Each modality provided detailed information on the coronary artery lesion. As in our case, OCT findings of recanalized thrombi showed a “spider web” or “honeycomb” pattern [ 6 8 ]. Since the irregularity of the recanalized thrombotic lesion on coronary angiography was mild but contained multiple lumens, the guidewire could easily have aberrantly crossed into a small channel, making the guidewire difficult to pass through the lesion.…”
Section: Discussionsupporting
confidence: 53%
“…Each modality provided detailed information on the coronary artery lesion. As in our case, OCT findings of recanalized thrombi showed a “spider web” or “honeycomb” pattern [ 6 8 ]. Since the irregularity of the recanalized thrombotic lesion on coronary angiography was mild but contained multiple lumens, the guidewire could easily have aberrantly crossed into a small channel, making the guidewire difficult to pass through the lesion.…”
Section: Discussionsupporting
confidence: 53%
“…A positive LAA, as in our patient, increases the risk of AMI by 5.5%, and the risk for angina pectoris by 2.7%. 8,9 Similarly, the IgG isotype of anticardiolipin (aCL) is strongly atherogenic and associated with worse cardiovascular outcomes, although this antibody was not present in our patient. In the end, all individual aPLs increase the risk for thrombosis and atherosclerosis.…”
Section: Discussionmentioning
confidence: 60%
“…The relative roles of coronary thrombosis and of coronary atherosclerosis in patients with APLS and/or SLE have not yet been thoroughly studied [21]. On the other hand, the issue of percutaneous coronary interventions (PCI) and CABG in patients with SLE and ACS needs further assessment because of equivocal data with regard to their appropriateness and effectiveness and increased associated risks [22].…”
Section: Discussionmentioning
confidence: 99%