Intravascular optical coherence tomography on a beating heart model

Lamouche, Guy; Dufour, M.; Hewko, Mark; Vergnole, Sébastien; Gauthier, Bruno; Bisaillon, Charles-Etienne; Monchalin, Jean‐Pierre; Sowa, Michael G.

doi:10.1117/1.3475960

Cited by 9 publications

(11 citation statements)

References 21 publications

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“…15 We used a wavelength-swept laser source (Santec, HSL2000) operating with a sweep rate of 30 kHz and a sweep range of over 110 nm around 1.31 μm wavelength to provide a measured axial resolution of about 12 μm in air. The catheter probe was designed to provide a spot size of 35 μm in diameter at a radial distance of about 2 mm in water.…”

Section: Methodsmentioning

confidence: 99%

“…Nevertheless, the only relevant imaging conditions are those were the balloon is close to or in contact with the artery wall. If only a thin layer of blood sits between the balloon exterior surface and the artery wall, the inner artery wall structures can still be observed, 15 allowing segmentation to be performed. In a recent work, we performed balloon inflation control in the near in vivo conditions provided by a beating heart setup.…”

Section: Remaining Challengesmentioning

confidence: 99%

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Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

Azarnoush

Vergnole

Pazos³

et al. 2012

J. Biomed. Opt.

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Abstract. We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was performed to extract the inner and outer diameters of the phantoms at various pressures. The goal for the second scenario was twofold. First, we investigated the IVOCT capability to monitor a more complex balloon inflation process. The balloon was in a folded state prior to inflation. This allowed studying two stages of deformation: during balloon unfolding and during balloon expansion. Second, we investigated IVOCT capability to monitor the deformation in a three-layer phantom used to better mimic a true artery. So, not only were the IVOCT images processed to provide the inner and outer diameters of the phantom, but the layer thicknesses were also determined. In both scenarios, IVOCT monitoring revealed to be very efficient in providing relevant information about the phantom deformation during balloon inflation. © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).

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Section: Methodsmentioning

confidence: 99%

Section: Remaining Challengesmentioning

confidence: 99%

Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

Azarnoush

Vergnole

Pazos³

et al. 2012

J. Biomed. Opt.

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“…After the overmoulding process, the three layers of these phantoms had the following formulations: The multilayer phantoms were imaged with our custom built IV-OCT system. The system has been described in a previous publication [4]. Fig.…”

Section: Shaft (Id) Tube (Od) Housingsmentioning

confidence: 99%

Poly(vinyl alcohol) cryogel, multi-layer artery phantoms for optical coherence tomography

et al. 2011

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“…Details about the IVOCT system and about the OCT catheter can be found in Ref. [1], while the use of IVOCT to monitor balloon inflation is described in Ref. [2].…”

Section: Ivoct Systemmentioning

confidence: 99%

“…Video 1 shows the IVOCT monitoring of the inflation of an angioplasty balloon within a coronary artery obtained in a beating heart setup [1]. After the balloon is sufficiently inflated to fill the lumen, any further inflation cause a deformation of the artery wall.…”

Section: Introductionmentioning

confidence: 99%

Assessing mechanical properties with intravascular or endoscopic optical coherence tomography

et al. 2011

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Assessing mechanical properties with intravascular or endoscopic optical coherence tomography Lamouche, G.; Azarnoush, H.; Vergnole, S.; Pazos, V.; Bisaillon, C.-E.; Debergue, P.; Boulet, B.; Diraddo, R. ABSTRACTWe explore the potential of intravascular or endoscopic optical coherence tomography (OCT) to extract relevant mechanical properties of a tissue deformed by an inflating balloon. Tubular OCT phantoms with different mechanical properties are fabricated. The phantoms are deformed by an inflating balloon, and the deformation is monitored with OCT. A quantitative description of the phantom deformation is obtained by segmenting the OCT images. Two strategies to extract the mechanical properties from this quantitative data are presented: by comparing to a finite-element simulation and by performing a mechanical analysis.

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Intravascular optical coherence tomography on a beating heart model

Cited by 9 publications

References 21 publications

Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

Poly(vinyl alcohol) cryogel, multi-layer artery phantoms for optical coherence tomography

Assessing mechanical properties with intravascular or endoscopic optical coherence tomography

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