Intravascular Papillary Endothelial Hyperplasia of the Pineal Region: A Case Report and Review of the Literature

Retzlaff, Amber A.; Arispe, Karen; Cochran, Elizabeth J.; Zwagerman, Nathan T.

doi:10.1016/j.wneu.2019.09.022

Cited by 8 publications

(3 citation statements)

References 38 publications

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“…IPEH lesions appear circumscribed with variable density on computed tomography (CT), hypo-to iso-intensity on T1WI, and iso- to hyperintensity on T2WI with obvious enhancement [ 1 ]. In this case, the US features of the spleen IPEH showed a well-defined, round heterogeneous mass with uneven internal echoes, strong, dotted echoes and no sound behind.…”

Section: Discussionmentioning

confidence: 99%

“…It is accompanied by papillary structures associated with thrombi and is considered to be the result of endothelial cell proliferation after thrombus recanalization. IPEH has been reported to account for approximately 2% of vascular tumors [ 1 , 2 ]. It was first proposed by Pierre Masson in 1923, when he thought it was a type of vascular endothelial cell proliferation with a tumor-like nature; thus, it is also known as Masson's pseudoangiosarcoma [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…IPEH can occur at any age and is more common among women [ 4 ]. It occurs in the skin of the head, neck, trunk, and cheek, as well as in the subcutaneous tissue of the nasal cavity, oral cavity, pharynx, larynx, and digestive tract [ 1 – 5 ]. Diagnosis is confirmed by histopathological analysis.…”

Section: Introductionmentioning

confidence: 99%

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Intravascular papillary endothelial hyperplasia of the spleen in a child: a case report

Huang

Zhu

et al. 2022

BMC Med Imaging

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Background Intravascular papillary endothelial hyperplasia (IPEH) is a vascular tumor characterized by the proliferation of endothelial cells with papillary formation. It is a rare benign condition affecting the head and neck. Currently, no cases of IPEH of the spleen have been reported. Here, we report a case of IPEH of the spleen in a child and discuss its clinical manifestations, imaging features, and surgical treatment. Case presentation A 5-year-old female presented with a 4-month-old tumor in the left upper abdomen, abdominal pain, and constipation. She underwent radiography, barium enema, US, and MRI. A solid space-occupying mass was found in the left abdominal cavity on preoperative imaging, and it was diagnosed as angiosarcoma. The lesion was surgically resected. Histopathological analysis was consistent with IPEH. Conclusion Clinicians should consider the possibility of IPEH in patients presenting with tumors in the spleen, which is curable by surgical resection. Malignant vascular tumors must be excluded in the differential diagnosis of IPEH to prevent misdiagnosis and inappropriate overtreatment.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%