Intravascular Two-Dimensional Catheter Ultrasound: Clinical Studies In The Periphery

Yock, Paul G.; Linker, David T.; Arenson, J.; Thapliyal, Hira V.; Sæther, Oddbjørn; White, Neal; Angelsen, B. A. J.

doi:10.1117/12.952181

Cited by 7 publications

(5 citation statements)

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“…Initial studies were performed using intra-operative epicardial probes [7,8]. More recently, catheter mounted transducers have allowed real time percutaneous transluminal imaging in conscious patients [9][10][11][12]. We, and others, have reported good correlation between ultrasound images and histologic vessel sections [13][14][15], the potential for angioplasty and atherectomy guidance [16][17][18], the ability to visualize thrombus [19] and intimal flaps [20] and the capacity to study beat-to-beat changes in arterial cross-sectional area [21].…”

Section: Introductionmentioning

confidence: 99%

Clinical percutaneous imaging of coronary anatomy using an over-the-wire ultrasound catheter system

et al. 1989

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This manuscript describes initial applications of a unique new intravascular ultrasound imaging catheter. This 5.5F catheter uses an over-the-wire design and incorporates a phased array transducer at its tip. There are no moving parts. A 360 degree image is produced perpendicular to the catheter axis using a 20 MHz center frequency. A dedicated minicomputer is used for initial image processing, as well as enhancement and analysis. Initial studies using phantoms demonstrated excellent accuracy for linear dimensions (r = 0.99, range 3.0 to 7.6 mm, image = 1.0 phantom + 0.1). Serial imaging of the same arterial segment in vitro showed good reproducibility (coefficients of variance 2.5-5.2%). Likewise, intra- and inter-observer variability in image analysis was minimal (r = 0.92-0.99). Initial in vivo studies were performed in dogs. The catheter was easily passed over a wire into mesenteric, cerebral and coronary vessels without evidence of significant vessel trauma. Subsequently, 20 patients had percutaneous coronary imaging performed during cardiac catheterization. Cardiac motion was rarely a problem and acceptable images were obtained in all but two patients. Areas of calcification, mild stenoses, branching vessels and graft atherosclerosis could be identified. We conclude that intracoronary ultrasound imaging will be useful for assessing vascular pathology, for studying both rapid change in vessel size as well as chronic progression or regression of atherosclerosis, and for assisting with new therapeutic interventions.

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Section: Introductionmentioning

confidence: 99%

Clinical percutaneous imaging of coronary anatomy using an over-the-wire ultrasound catheter system

et al. 1989

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“…Early clinical trials, most published in preliminary form, have demonstrated that catheter ultrasound can detect significant features of vascular pathology that are inaccessible by conventional techniques. [1][2][3][4][5][6] The favorable outcome of recent pilot studies in human coronary arteries suggests that catheter ultrasound may be useful clinically in assessing coronary lesions and guiding catheter-based interventions. 7,8 Initial Development…”

Section: Editorial Comment Intravascular Ultrasoundmentioning

confidence: 99%

Intravascular ultrasound. Looking below the surface of vascular disease.

Yock

Linker

1990

Circulation

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“…Enquanto isso, paralelamente aos estudos conduzidos por Palmaz e Schatz (1987) para o tratamento percutâneo da doença arterial coronariana (DAC), outros autores, entre eles Paul Yock et al (1988), apresentam, na 37th Annual Scientific Session of the American College of Cardiology, 3 o primeiro estudo com resultados relacionados à utilização do ultrassom intracoronário (USIC) como uma ferramenta de excelente qualificação para o diagnóstico da DAC. Com essa nova tecnologia, seria possível avaliar a morfologia da superfície do vaso.…”

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“…Meanwhile, in parallel with the studies conducted by Palmaz and Schatz (1987) for the percutaneous treatment of coronary artery disease (CAD), other authors, including Paul Yock’s et al (1988), presented the first study related to the use of intracoronary ultrasound (ICUS) as an excellent qualification tool for the diagnosis of CAD at the 37th Annual Scientific Session of the American College of Cardiology. 3 This new technology would allow for the evaluation of the vessel surface morphology.…”

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confidence: 99%