2005
DOI: 10.1053/j.jvca.2005.03.006
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Intravenous Acetaminophen Reduced the Use of Opioids Compared With Oral Administration After Coronary Artery Bypass Grafting

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Cited by 108 publications
(78 citation statements)
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“…Thus, these results are parallel with the conclusion of Petterson et al, suggesting that additional intravenous administration of paracetamol provides a limited decrease in opioid dose in postoperative pain, which is not sufficient to achieve a better side-effect profile [16].…”
Section: Discussionsupporting
confidence: 79%
“…Thus, these results are parallel with the conclusion of Petterson et al, suggesting that additional intravenous administration of paracetamol provides a limited decrease in opioid dose in postoperative pain, which is not sufficient to achieve a better side-effect profile [16].…”
Section: Discussionsupporting
confidence: 79%
“…However, their safety profile and effectiveness as sole agents for pain management have not been adequately studied in critically ill patients. IV acetaminophen has been recently approved for use in the United States and has been shown to be safe and effective when used in conjunction with opioids for postoperative pain in surgical ICU patients following major or cardiac surgery (80,(86)(87)(88)(89). IV acetaminophen has been recently approved for use in the United States and has been shown to be safe and effective when used in conjunction with opioids for postoperative pain in surgical ICU patients following major or cardiac surgery (80,(86)(87)(88)(89).…”
Section: Treatment Of Painmentioning
confidence: 99%
“…Intravenously administered acetaminophen is now approved for use in the USA. Its safety and effectiveness as an adjunct to opioids have been demonstrated in ICU patients after major general [41] and cardiac surgery, but it may not be necessary unless enteral administration is contraindicated [49]. Ketamine, an anesthetic and analgesic agent, has been used in ICU patients to help prevent or reduce opioid tolerance and to provide pain relief, especially when pain is refractory to opioids and other agents [50, 51].…”
Section: What Are Current Strategies For Managing Symptoms During Crimentioning
confidence: 99%