Intravenous estrogen is not proven effective for abnormal uterine bleeding: guidelines are based on flawed evidence

Abstract

Simmer S. Intravenous estrogen is not proven effective for abnormal uterine bleeding: guidelines are based on flawed evidence. Clin.

Abnormal uterine bleeding guidelines and clinical practice are based on poor quality evidence

“…4,5 Tranexamic acid, an antifibrinolytic, has not yet specifically been analyzed in a RCT for acute AUB. 3,6 In order to ensure best practice in the case of A.F., medroxyprogesterone acetate and combination OCs as studied in a RCT by Munro et al and cited in ACOG recommendations was evaluated as an alternative treatment to Premarin® and forms the basis of this critical appraisal.…”

Differing cognitive strategies between evidence-based medicine and evidence-based practice

“…They become obsolete and vary widely in validity. 6 In order to practice quality medicine, doctors need an evidence-based diet, a term I coined for habitual review of relevant research related to our patients. Additionally, doctors need to master another ACGME competency, practice-based learning.…”