2014
DOI: 10.1177/1708538114552839
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Intravenous iloprost for treatment of critical limb ischemia in patients unsuitable for revascularization

Abstract: One-week treatment with iloprost may provide both long lasting symptomatic benefit and may improve hemodynamic parameters, which were shown to predict future amputation.

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Cited by 6 publications
(3 citation statements)
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“…26 In previous studies, the duration of iloprost administration for CLI varied between one and four weeks, with positive outcomes in terms of symptomatic improvement and decreased amputation risk in all publications. 27,28 We believe that angioplasty procedures on peripheral vessels are relatively challenging. Traditionally, most angioplasty procedures are performed for coronary vessels, while its use in peripheral vessels has only recently gained more widespread popularity.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…26 In previous studies, the duration of iloprost administration for CLI varied between one and four weeks, with positive outcomes in terms of symptomatic improvement and decreased amputation risk in all publications. 27,28 We believe that angioplasty procedures on peripheral vessels are relatively challenging. Traditionally, most angioplasty procedures are performed for coronary vessels, while its use in peripheral vessels has only recently gained more widespread popularity.…”
Section: Discussionmentioning
confidence: 99%
“…26 In previous studies, the duration of iloprost administration for CLI varied between one and four weeks, with positive outcomes in terms of symptomatic improvement and decreased amputation risk in all publications. 27,28…”
Section: Discussionmentioning
confidence: 99%
“…It is also used as a regulatory element in IR injury for inhibition of the immune system and reduction of free oxygen radicals (4). Iloprost has shown favorable results in critical limb ischemia (5). It also decreases neutrophil adhesion and platelet aggregation, helping to prevent organ damage in IR injury (6).…”
Section: Introductionmentioning
confidence: 99%