Intravenous Immunoglobulin Therapy

Sulk, Mathias; Goerge, Tobias; Luger, Thomas A.

doi:10.1016/b978-0-323-61211-1.00036-x

Cited by 1 publication

(1 citation statement)

References 147 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We theorize that IVIG may have accelerated catabolism of ETN via saturation of the neonatal Fc receptor and neutralized ETN via anti-idiotypic antibodies that could bind to the Fc portion of ETN. 19 – 22 Peak level of ETN occurs 2 days after injection. 22 ETN is given after IVIG for resistant Kawasaki disease at doses of 0.8 mg/kg SC within 24 h then repeated at days 7 and 14 which was the dosing we adopted for our patient’s second dose.…”

Section: Discussionmentioning

confidence: 99%

Reactive infectious mucocutaneous eruption – repeat etanercept after intravenous immunoglobulin: A case report

Tonkin

Ladha

Johnson

et al. 2022

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

Reactive infectious mucocutaneous eruption is a recently distinguished mucosal-predominant blistering eruption triggered by respiratory infections. We describe a previously healthy 11-year-old Black female with rapidly progressive mucocutaneous blistering after prodromal respiratory infection symptoms. Reactive infectious mucocutaneous eruption was suspected and treated with systemic corticosteroids followed by etanercept. Twenty-four hours after etanercept, the diagnosis of multisystem inflammatory syndrome in children was raised and intravenous immunoglobulin was given. Rapidly worsening mucocutaneous disease ensued but was controlled by a second dose of etanercept. Our case highlights the following: (1) the novel observation of possible interaction/neutralization of etanercept by intravenous immunoglobulin, (2) the challenging differential diagnosis of multisystem inflammatory syndrome in children for reactive infectious mucocutaneous eruption patients in the Coronavirus disease 2019 (COVID-19) pandemic, and (3) the role of early treatment to prevent dyspigmentation.

show abstract