Intravenous Iron in Inflammatory Bowel Disease

The role of intravenous iron in anemia management and transfusion avoidance

“…55 Published prospective data on the efficacy of IV iron in IBD is limited to iron sucrose. 56 Gasche and coworkers 38 randomly assigned 40 patients with IBD and anemia receiving 200 mg of IV iron sucrose to either EPO or placebo. All patients were either refractory or intolerant to oral iron.…”

The role of intravenous iron in anemia management and transfusion avoidance

“…In patients with IBD, oral iron therapy is associated with severe side effects, is poorly absorbed, has limited efficacy, and has actually been associated with worsening of the bowel symptoms 55 . Published prospective data on the efficacy of IV iron in IBD is limited to iron sucrose 56 . Gasche and coworkers 38 randomly assigned 40 patients with IBD and anemia receiving 200 mg of IV iron sucrose to either EPO or placebo.…”

Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor- treatment

“…Anemia is a common hematologic complication of inflammatory bowel disease, occurring in 6% to 74% of patients. 1 The wide range in the reported prevalence of anemia is related to differences in study design (e.g. investigation of patients at presentation or during the course of the disease, inpatients or out-patients), in the criteria used to define anemia, and to the increasing awareness of the disease and improved treatments, leading to earlier diagnosis and lower rates of anemia observed in more recent studies.…”