2024
DOI: 10.1136/bcr-2023-256417
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Intravenous lipid emulsion for a life-threatening prothipendyl intoxication

Anne Meunier,
Pierre Goffin,
Marine Deville
et al.

Abstract: Prothipendyl, a lipophilic neuroleptic drug, requires a careful dosage regimen due to its potential side effects, including life-threatening arrhythmias.This report outlines a case of severe prothipendyl intoxication, its management and the successful utilisation of Intralipid, an intravenous lipid emulsion, in treating ventricular arrhythmia postmassive prothipendyl ingestion. Additionally, the mechanism of action of Intralipid and the rebound concentration of the lipophilic drug in such scenarios are discuss… Show more

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