Intravenous regional analgesia for surgery of the limbs in goats

Babalola, G. O.; Oke, B. O.

doi:10.1080/01652176.1983.9693895

Cited by 15 publications

(5 citation statements)

References 11 publications

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“…Intravenous regional anaesthesia has also been described in small ruminants (Babalola & Oke, 1983) and dogs (Kiipper, 1977). Studies using radioisotopes (Lillie et al, 1984) have shown that the injected compounds diffused out of the vascular bed and became distributed rapidly into the muscles and nerves.…”

Section: Introductionmentioning

confidence: 99%

Single‐dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection

Gagnon

Jg²,

Papich

et al. 1994

Vet Pharm & Therapeutics

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The pharmacokinetic properties of cefazolin in the synovial fluid of the tibiotarsal joint were determined in 10 healthy mature cattle after intravenous regional injections of 250 mg cefazolin. A pneumatic tourniquet was positioned proximal to the tibiotarsal joint and the intravenous injection was performed distal to the tourniquet. Synovial fluid concentrations of cefazolin increased in the first 30 min and fluctuated between 54.7 +/- 11.0 micrograms/ml (mean +/- SEM) and 73.2 +/- 13.2 micrograms/ml in the following 90 min while the tourniquet remained inflated. After tourniquet removal, synovial fluid concentration-time curves followed first-order one-compartment model decay in most of the animals with an elimination half-life of 0.82 h (harmonic mean). Therapeutic concentrations of cefazolin in the synovial fluid of normal joints were reached and this injection technique could be used as an alternative to systemic administration of antibiotics to provide adequate concentrations in a localized area.

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Section: Introductionmentioning

confidence: 99%

Single‐dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection

Gagnon

Jg²,

Papich

et al. 1994

Vet Pharm & Therapeutics

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“…Regional nerve block analgesia is of obvious advantage in ruminants and various methods are available. In small ruminants, these methods are less easily applied than in their larger counterpart, obviously because of small size (Babalola and Oke, 2011).…”

Section: Tablementioning

confidence: 99%

Review on Commonly Used Veterinary Anesthetic Drugs in Small Ruminants

Mekonnen,

Abderehman,

Seyaka

2023

VSSR

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Now a day a variety of drugs are on use for providing anesthesia in animals. Small ruminants, due to their anatomy and physiology, are not suitable for many of the anesthetic drugs. With strict consideration, some drugs are commonly used in these animals. Anesthetic drugs classified based on their action and efficacy. The commonly used local anesthetic agents include procaine, lidocaine and bupivacaine. Understanding the pharmacology of local anesthetics enables the anesthetists to predict the potency, speed of onset, duration of action and safety of a specific drug in a given clinical situation. A local anaesthetic disrupts ion channel function within the neuron cell membrane preventing the transmission of the neuronal action potential while general anesthetics like ketamine disrupt pathways within the cerebrum and stimulates the reticular activating center. Local anaesthetics affect all excitable tissues in the body, so toxicity can occur when sufficient amounts of the drug are absorbed into the circulation. General anesthesia (GA) is not commonly used in small ruminants as its administration results in several side effects such as; ruminal tympany, regurgitation of reticuloruminal contents, aspiration of refluxed material or saliva, hypoventilation, hypotension and fluid and electrolyte imbalances. Ketamine (injectable) is a commonly used general anaesthetic agent in veterinary practice. Injectable anesthetics offer the advantage of requiring less expensive equipment. Isoflurane (inhalant) provides a very rapid and smooth induction and recovery. Pre-anesthetic medications are used to decrease fear and apprehension, aid in restraint, decrease the amount of other anesthetic agents required and decrease side effects of induction drugs. These drugs are metabolized by the liver and excreted by the kidneys. Monitoring vital signs continuously during anesthesia will provide early warning of potential problems and emergencies that may be averted by appropriate and quick corrective actions.

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“…47,68,150 Additionally, in comparison to both general anesthesia as well as other local nerve blocks 32 the number of injection sites is minimized, the procedure is rapidly accomplished, development of and recovery from analgesia is speedy, relatively small volumes of anesthetic are used, and advanced anatomic knowledge and technical skills are not required. 10 Furthermore, some control can be exerted over the duration of action of the local anesthetic. 156 Because of these factors, tissue trauma is minimized and risk of introducing contamination into surrounding tissue structures is similarly reduced.…”

Section: Use Of Local Anesthetics In Rivpmentioning

confidence: 99%

Review of digital anatomy, infectious causes of lameness, and regional intravenous perfusion in cattle

Simpson

Streeter

Jones

et al. 2020

The Bovine Practitioner

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Digital disorders in cattle constitute the majority of lameness issues that bovine practitioners will encounter. Treatment of many digital infections in cattle can be facilitated in part by regional limb perfusions of either local anesthetics, antibiotics, or both. This article reviews infectious causes of digital disease, relevant clinical anatomy, use of various perfusates and tourniquet types in regional intravenous perfusions in cattle, and potential complications associated with the procedure.

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Intravenous regional analgesia for surgery of the limbs in goats

Cited by 15 publications

References 11 publications

Single‐dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection

Single‐dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection

Review on Commonly Used Veterinary Anesthetic Drugs in Small Ruminants

Review of digital anatomy, infectious causes of lameness, and regional intravenous perfusion in cattle

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