Intravenous rocuronium 0.3 mg/kg improves the conditions for tracheal intubation in cats: a randomized, placebo-controlled trial

Sakai, Daniel M.; Zornow, Kailee Anne; Campoy, Luis; Cable, C G; Appel, Leslie D.; Putnam, Holly J; Martin‐Flores, Manuel

doi:10.1177/1098612x18754425

Cited by 7 publications

(1 citation statement)

References 21 publications

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“…In a phase II trial, a three-drug combination therapy (GCS therapy) with S-1 added to GEM/CIS therapy was tried, the results were excellent, with a response rate of 24% and a median OS of 16.2 months [ 195 ]. The KHBO1401 phase III trial comparing GCS and GEM/CIS therapy was subsequently conducted, proving the superiority of GCS therapy over GEM/CIS therapy [ 196 ]. GCS therapy is now being positioned as a new treatment option.…”

Section: Cisplatin and Treatment Of Cholangiocarcinomamentioning

confidence: 99%

Cisplatin in Liver Cancer Therapy

Hamaya

Oura

Morishita

et al. 2023

IJMS

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Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is often diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as transarterial chemoembolization (TACE) and hepatic arterial infusion chemotherapy (HAIC) are used to treat advanced HCC. TACE and HAIC have long been the standard of care for patients with unresectable HCC but are limited to the treatment of intrahepatic lesions. Systemic chemotherapy with doxorubicin or chemohormonal therapy with tamoxifen have also been considered, but neither has demonstrated survival benefits. In the treatment of unresectable advanced HCC, cisplatin is administered transhepatic arterially for local treatment. Subsequently, for cisplatin-refractory cases due to drug resistance, a shift to systemic therapy with a different mechanism of action is expected to produce new antitumor effects. Cisplatin is also used for the treatment of liver tumors other than HCC. This review summarizes the action and resistance mechanism of cisplatin and describes the treatment of the major hepatobiliary cancers for which cisplatin is used as an anticancer agent, with a focus on HCC.

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Section: Cisplatin and Treatment Of Cholangiocarcinomamentioning

confidence: 99%