Intravesical Instillation of Capsaicin in Urology: A Review of the Literature

Sèze, M. de; Wiart, L.; Ferrière, Jean-Marie; Sèze, Mathieu Panchoa de; Joseph, Pierre-Alain; Barat, M.

doi:10.1159/000020004

Cited by 68 publications

(7 citation statements)

References 23 publications

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“…It acts through an ion channel known as vanilloid receptor subtype 1 [19, 20, 24]. Activation of this receptor will excite and then selectively desensitize afferent fibers [19, 20]. The desensitization of the afferent fibers in the present study has prevented the contralateral testis from the adverse effects of ipsilateral testicular torsion.…”

Section: Discussionmentioning

confidence: 92%

“…Capsaicin is a neurotoxin which is an extract of Mexican red peppers [19, 20]. It can be administered via intravenous or intraperitoneal routes [23].…”

Section: Discussionmentioning

confidence: 99%

“…It can also be applied topically [24]. It acts through an ion channel known as vanilloid receptor subtype 1 [19, 20, 24]. Activation of this receptor will excite and then selectively desensitize afferent fibers [19, 20].…”

Section: Discussionmentioning

confidence: 99%

“…Capsaicin is a neurotoxin which causes release of calcitonine gene–related peptide (CGRP) and substance P and then selectively desensitizes afferent fibers [19, 20]. The desensitization of the afferent fibers may prevent contralateral testis from the adverse effects of ipsilateral testicular torsion.…”

Section: Introductionmentioning

confidence: 99%

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Capsaicin in Albino Rats Prevents Contralateral Testis from the Damaging Effects Posed by Ipsilateral Testis That Underwent Torsion

Sarioğlu

Gedikoğlu²,

Bingöl-Koloğlu

et al. 2001

Eur Urol

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Section: Discussionmentioning

confidence: 92%

“…Capsaicin is a neurotoxin which is an extract of Mexican red peppers [19, 20]. It can be administered via intravenous or intraperitoneal routes [23].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Capsaicin in Albino Rats Prevents Contralateral Testis from the Damaging Effects Posed by Ipsilateral Testis That Underwent Torsion

Sarioğlu

Gedikoğlu²,

Bingöl-Koloğlu

et al. 2001

Eur Urol

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“…On the other hand, a capsaicin hydrogel was effective by decreasing bladder contraction; however, it failed to produce overflow incontinence. Intravesical capsaicin application induced detrusor contractions and reduced bladder volume threshold to reflex micturition in humans (de Sèze et al, 1999;Fowler, Jewkes, McDonald, Lynn, & de Groat, 1992;Patowary et al, 2017;Sharma et al, 2013).…”

Section: Urinary System Disorders Renal Failure and Vulvar Vestibulmentioning

confidence: 95%

Capsicum annuum(hot pepper): An ancient Latin‐American crop with outstanding bioactive compounds and nutraceutical potential. A review

Hernández-Pérez

Gómez-García

Valverde

et al. 2020

Comp Rev Food Sci Food Safe

162

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Hot pepper (Capsicum annuum) fruits, usually termed as chili, have been used since ancient times as food vegetables, flavoring ingredients, natural colorants, and in traditional medicines. Nowadays, a wide variation of sweet and pungent peppers are consumed worldwide in a large variety of forms. Interestingly, the most important hot pepper at the global level in commercial terms is C. annuum with a high number of varieties. This review compares C. annuum to other Capsicum species for plant agronomic traits, biochemical composition, the content of capsaicin and capsaicinoids and their nutraceutical and medical potentialities, and the effects of processing on quality and key components of the fruit, among other aspects. Chili contains important levels of pigments (i.e., chlorophyll, anthocyanin, and lutein) with potential health benefits; it also contains additional outstanding health-promoting chemical compounds, such as vitamins, minerals, flavonoids, carotenoids, and capsaicinoids, in general. And capsaicin, the major active compound responsible for the pungent taste of these species has been proven to have a positive role in health. We report here on how dietary chili and capsaicinoids consumption, especially capsaicin, are involved in body weight reduction and their potential antiobesity effects, in urinary disorders, as well as antioxidants, antimicrobial, anticancer, and analgesic capacity. Selected characteristics of processing for the fruit preservation on its quality and content of these compounds are described as well. However, additional clinical research on the mechanism of action and efficacy of frequent capsaicinoid consumption on human health is needed.

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Intravesical glucidic capsaicin versus glucidic solvent in neurogenic detrusor overactivity: A double blind controlled randomized study

Sèze¹,

Gallien

Denys

et al. 2006

Neurourology and Urodynamics

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Intravesical Instillation of Capsaicin in Urology: A Review of the Literature

Cited by 68 publications

References 23 publications

Capsaicin in Albino Rats Prevents Contralateral Testis from the Damaging Effects Posed by Ipsilateral Testis That Underwent Torsion

Capsaicin in Albino Rats Prevents Contralateral Testis from the Damaging Effects Posed by Ipsilateral Testis That Underwent Torsion

Capsicum annuum(hot pepper): An ancient Latin‐American crop with outstanding bioactive compounds and nutraceutical potential. A review

Intravesical glucidic capsaicin versus glucidic solvent in neurogenic detrusor overactivity: A double blind controlled randomized study

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