Intravesical Instillation of Mitomycin C: A Cause of Delayed Bladder Perforation?

Penna, Marta; Mistry, Kiki; Pal, Pallavi; Chitale, Sudhanshu

doi:10.1155/2012/576519

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Penna et al 3 reported a 77-year-old Caucasian male who received an early MMC instillation after TURBT. This patient complained of urinary retention after the removal of an indwelling catheter.…”

Section: Discussionmentioning

confidence: 99%

A rare complication of intravesical early instillation of mitomycin C after TURBT

Hatem

Jörg

2019

Urology Case Reports

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The early intravesical Instillation of mitomycin C (MMC) is accepted as safe adjuvant therapy after TURBT by non-muscle- invasive bladder cancer if there is no perforation. In our case we report a female patient undergoing resection of papillary recurrent tumor on the anterior bladder wall. In the early postoperative period had the patient no complaints regarding to Instillation of MMC. The clinical manifestation of the necrosis of the anterior bladder wall appeared after one week requiring a long extended unsuccessful conservative therapy in order to save the bladder. Finally we performed a radical cystectomy. This complication is reported by some authors in literature.

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Section: Discussionmentioning

confidence: 99%

A rare complication of intravesical early instillation of mitomycin C after TURBT

Hatem

Jörg

2019

Urology Case Reports

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“…4 On the other hand, reporting major complications such as bladder perforation, perirectal abscesses, eosinophilic cystitis, and ureteral stenosis is limited to case reports. [5][6][7][8][9][10][11][12][13][14] In this case, we described our experience with bladder perforation after immediate intravesical instillation of doxorubicin.…”

Section: Discussionmentioning

confidence: 96%

“…On the other hand, reporting major complications such as bladder perforation, perirectal abscesses, eosinophilic cystitis, and ureteral stenosis is limited to case reports. 5 - 14 …”

Section: Discussionmentioning

confidence: 99%

Delayed Bladder Perforation Related to Immediate Single Dose Intravesical Doxorubicin Instillation After TURBT: A Case Report and Literature Review

Alrabadi

Abuhamad

Mansi

et al. 2021

Clin Med Insights Case Rep

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Introduction: Intravesical chemotherapy instillation immediately after tumor resection is a well-known practice in the management of non-muscle invasive bladder cancer. Despite being largely well tolerated in most cases, it is not devoid of severe and life-threatening complications. Case Presentation: We present an unusual case of bladder perforation that happened 2 weeks after bladder tumor resection. The patient had received single dose intra-vesical instillation of doxorubicin after TUR-BT. Conservative managements failed to achieve bladder healing; as a result, open surgical repair was performed. To the best of our knowledge, this is the first reported case of bladder perforation after intra-vesical doxorubicin instillation. Conclusion: The occurrence of such a rare serious complication in a mostly safe intervention must be taken into consideration. A high index of suspicion, timely management, and proceeding to more invasive surgical treatments when necessary are cornerstones in the management and preserving the bladder.

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Appendicovesical Fistula Following Transurethral Resection of Bladder Tumor With Mitomycin C

Feng

Rusnack

Kamiński

et al. 2016

Urology

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Intravesical Instillation of Mitomycin C: A Cause of Delayed Bladder Perforation?

Abstract: We present a case of bladder perforation secondary to intravesical instillation of mitomycin C following transurethral resection of bladder tumour (TURBT) and the role of early detection leading to successful conservative management. We also review the key relevant literature.

Cited by 3 publications

References 8 publications

A rare complication of intravesical early instillation of mitomycin C after TURBT

A rare complication of intravesical early instillation of mitomycin C after TURBT

Delayed Bladder Perforation Related to Immediate Single Dose Intravesical Doxorubicin Instillation After TURBT: A Case Report and Literature Review

Appendicovesical Fistula Following Transurethral Resection of Bladder Tumor With Mitomycin C

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