1998
DOI: 10.1159/000030333
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Intravesical Instillation of Mitomycin-C in 242 Patients with Superficial Bladder Cancer at High Risk of Recurrence: Long-Term Results

Abstract: Objective: The present study evaluated the long-term results of intravesical mitomycin C (MMC) instillation after transurethral resection (TUR) in 242 consecutive patients with superficial bladder cancer at high risk of recurrence (stage Ta, grade 1–3, or stage T1, grade 1 and 2, primary multiple or recurrent tumor). Materials and Methods: 242 patients were treated with weekly instillations of 40 mg MMC for 8 weeks after TUR. Tumor-free patients then followed a maintenance course with monthly instillations for… Show more

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Cited by 8 publications
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“…Intravesical MMC has been evaluated in humans with low grade superficial TCC and high‐grade carcinoma in situ 16–19 . Complete response rates in humans have exceeded 50% with no patients having any reported severe systemic toxicosis.…”
mentioning
confidence: 99%
“…Intravesical MMC has been evaluated in humans with low grade superficial TCC and high‐grade carcinoma in situ 16–19 . Complete response rates in humans have exceeded 50% with no patients having any reported severe systemic toxicosis.…”
mentioning
confidence: 99%