Intravesical pressure: A new prognostic indicator in congenital diaphragmatic hernia

Abraham, Mohan; Viswanath, Naveen; Ramakrishnan, P.; Bindu, S; Kedari, Prashant M.; Naaz, Aisha; Rahman, Lukman O Abdur; Nasir, Abdulrasheed A; Mohan, S.; Shivji, R; Sasidharan, P

doi:10.4103/0971-9261.86864

Cited by 6 publications

(5 citation statements)

References 5 publications

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“…The mode of valve ablation in this study was valve ablation with Mohan's valvotome which has been shown to be effective method for valve ablation with comparable results to that achieved through endoscopy (16,18,19). This has proved to be valuable in our centre where facility for endoscopic ablation is unavailable.…”

Section: Discussionmentioning

confidence: 87%

“…Mohan's valvotome have been found to be useful in valve ablation with comparable result with endoscopic valve ablation (16,18,19); Albeit, it may be associated with inadequacy of valve ablation (20) as the procedure is done blindly unlike endoscopic valve ablation which is usually performed under direct vision. In this study, there was failure of satisfactory ablation of valve in one of the patient which necessitated a repeat procedure.…”

Section: Challenges In Managementmentioning

confidence: 99%

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Posterior urethral valve: a retrospective review of cases and challenges of management in a low-resource centre

Ajao¹,

Abiola²,

Alao³

et al. 2018

Research Journal of Health Sciences

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Posterior urethral valves (PUV) diagnosis and management remain a major challenge in developing countries. We sought to review cases of PUV managed in our health centre and to highlight the challenges in its management. Methods: A retrospective analysis of patients with PUV managed over a 12month period. Data obtained from patients' medical records include: demography, clinical presentation, serum electrolytes, urea and creatinine, radiological diagnosis, initial management, surgical management and the outcome of management. Results: Eight patients were managed during the period under review. The median age was 26 months. The commonest clinical feature was recurrent fever. Three patients (37.5%) had renal insufficiency requiring peritoneal dialysis at initial presentation. Six patients (75%) had Mohan's valvotomy while two (25%) died before valve ablation. One patient (12.5%) died a month after valve ablation from renal failure, while one (12.5%) had residual valve requiring a repeat valve ablation. Post-operative complication of urosepsis occurred in two patients (25%). Conclusions: Physicians should have a high index of suspicion for PUV in boys who present with recurrent fever or urinary tract infections. Screening for foetal anomalies during routine antenatal maternal ultrasonography will improve prenatal diagnosis of this condition.

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Section: Discussionmentioning

confidence: 87%

Section: Challenges In Managementmentioning

confidence: 99%

Posterior urethral valve: a retrospective review of cases and challenges of management in a low-resource centre

Ajao¹,

Abiola²,

Alao³

et al. 2018

Research Journal of Health Sciences

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“…have shown the use of measuring intravesical pressure as a prognostic marker in CDH. [ 6 ] There are other various indirect methods of measurement of IAP such as CVP and peak inspiratory pressure. Each of the methods has its own advantages and disadvantages.…”

Section: Discussionmentioning

confidence: 99%

Intragastric pressure: Useful indicator in the management of congenital diaphragmatic hernia

Mandal

Halder

Barman

et al. 2016

J Indian Assoc Pediatr Surg

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Aims:To assess the role of measuring of intragastric pressure (IGP) during closure of congenital diaphragmatic hernia.Materials and Methods:Thirty-two cases were included in the study (August 2008 to February 2014), and IGP has been measured intraoperatively during closure.Result:Patients were categorized in group A (15 patients), group B (14 patients) and group C (3 patients). In group C, IGP was more than 30 cm of water pressure and all of tehm required creation of ventral hernia and ventilator support.Conclusion:Measurement of IGP as an objective, noninvasive and simple method to evaluate intra-abdominal pressure and prevention of abdominal compartment syndrome and intraoperative IGP value determines the types of abdominal closure.

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“…IAP Measurement IAP was measured by intravesical manometry as described previously (13). The urinary bladder was emptied, and sterile normal saline was instilled into the bladder with a volume of 1 ml/kg.…”

Section: Patientsmentioning

confidence: 99%

Hypoxic renal injury in newborns with abdominal compartment syndrome (clinical and experimental study)

et al. 2017

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BackgroundSurgical treatment for gastroschisis and congenital diaphragmatic hernia (CDH) commonly leads to abdominal compartment syndrome (ACS) associated with hypoxic renal injury. We hypothesized that measurement of urinary and serum concentrations of vascular endothelial growth factor (VEGF), π-glutathione S-transferase (π-GST), and monocyte chemoattractant protein-1 (MCP-1) may serve for noninvasive detection of hypoxic renal injury in such patients.MethodsIntra-abdominal pressure (IAP), renal excretory function, and the biomarker levels were analyzed before, 4, and 10 days after surgery. Association between the biomarker levels and renal histology was investigated using an original model of ACS in newborn rats.ResultsFour days after surgery, IAP increased, renal excretory function decreased, and the levels of VEGF, π-GST, and MCP-1 increased, indicating renal injury. Ten days after surgery, IAP partially decreased, renal excretory function completely restored, but the biomarker levels remained elevated, suggesting the ongoing kidney injury. In the model of ACS, increase in the biomarker levels was associated with progressing kidney morphological alteration.ConclusionSurgical treatment for gastroschisis and CDH is associated with prolonged hypoxic kidney injury despite complete restoration of renal excretory function. Follow-up measurement of VEGF, π-GST, and MCP-1 levels may provide a better tool for noninvasive assessment of renal parenchyma in newborns with ACS.

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Intravesical pressure: A new prognostic indicator in congenital diaphragmatic hernia

Cited by 6 publications

References 5 publications

Posterior urethral valve: a retrospective review of cases and challenges of management in a low-resource centre

Posterior urethral valve: a retrospective review of cases and challenges of management in a low-resource centre

Intragastric pressure: Useful indicator in the management of congenital diaphragmatic hernia

Hypoxic renal injury in newborns with abdominal compartment syndrome (clinical and experimental study)

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