2017
DOI: 10.1111/aos.13547
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Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

Abstract: Symptomatic vitreomacular adhesion (sVMA) is defined as visual loss secondary to foveal damage from vitreomacular traction (VMT) and includes isolated VMT, impending macular hole (MH), and full-thickness MH with persisting vitreous attachment. Management options include pars plana vitrectomy (PPV), intravitreal ocriplasmin, intravitreal gas injection or observation. This synthesis of the literature aimed to assess the safety and efficacy of intravitreal gas for sVMA. Articles describing patients with VMT or MH… Show more

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Cited by 18 publications
(18 citation statements)
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“…Overall, the present study shows a potentially useful approach to obtain promising leads based on human Micro-plasmin that may be of clinical use in the near future, especially in thrombolytic therapies for ischemic stroke and also, possibly, intra-ocular applications [78].…”
Section: Discussionmentioning
confidence: 99%
“…Overall, the present study shows a potentially useful approach to obtain promising leads based on human Micro-plasmin that may be of clinical use in the near future, especially in thrombolytic therapies for ischemic stroke and also, possibly, intra-ocular applications [78].…”
Section: Discussionmentioning
confidence: 99%
“…This technique seems to be more effective than ocriplasmin injection as a primary treatment for vitreomacular traction, but its use for small macular holes with traction is not yet fully established [17] and a few contraindications to gas injection (mainly air travel and late-stage glaucoma) remain.…”
Section: Discussionmentioning
confidence: 99%
“…There are three commonly used management options for VMT – observation, vitreolysis and vitrectomy. There are also small clinical case series investigating the use of a gas bubble to treat VMT 14. The current standard of care in early stage VMT is observation, a strategy that is often justified for people with no or few symptoms and in the expectation that some cases may resolve spontaneously.…”
Section: Introductionmentioning
confidence: 99%