Intravitreal Ranibizumab Treatment for Advanced Familial Exudative Vitreoretinopathy With High Vascular Activity

Lyu, Jiao; Zhang, Qi; Xu, Yu; Zhang, Xiang; Fei, Ping; Zhao, Peiquan

doi:10.1097/iae.0000000000003122

Cited by 5 publications

(6 citation statements)

References 26 publications

(63 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(7) Check the EICAS, and there should be free of inerting system and relative system fault messages; (8) The airplane takes off normally and completes the flight as scheduled, and the rate of descent should meet the flight test requirements;…”

Section: Civil Aircraft Inerting System Performance Flight Test Methodsmentioning

confidence: 99%

“…Major manufacturers of commercial aircraft and integrators of inerting systems commonly utilize the Oxigraf oxygen concentration testing system. This system employs a patented technology based on diode laser absorption spectroscopy, enabling non-contact and real-time measurement of low-temperature gas [8] . It proves to be a valuable tool for analyzing the oxygen concentration in Jet-A aviation fuel and air mixtures [9][10] .…”

Section: Modification For Temperature Pressure and Oxygen Concentrati...mentioning

confidence: 99%

See 1 more Smart Citation

Application of sensors for civil aircraft inerting system performance flight test

Yue,

Zeng,

Xue

2024

Fourth International Conference on Sensors and Information Technology (ICSI 2024)

View full text Add to dashboard Cite

show abstract

Section: Civil Aircraft Inerting System Performance Flight Test Methodsmentioning

confidence: 99%

Section: Modification For Temperature Pressure and Oxygen Concentrati...mentioning

confidence: 99%

Application of sensors for civil aircraft inerting system performance flight test

Yue,

Zeng,

Xue

2024

Fourth International Conference on Sensors and Information Technology (ICSI 2024)

View full text Add to dashboard Cite

show abstract

“…Anti-VEGF treatment has demonstrated therapeutic efficacy in pediatric retinal diseases, including retinopathy of prematurity, Coats disease, incontinentia pigmenti, and familial exudative vitreoretinopathy . Anti-VEGF treatment can be used as a primary treatment or adjunct therapy . Anti-VEGF also helps accelerate the clearance of vitreous hemorrhage in proliferative diabetic retinopathy .…”

Section: Introductionmentioning

confidence: 99%

“…The proliferation of newly formed vessels, driven by VEGF, can result in vitreous hemorrhage and tractional retinal detachment. Anti-VEGF treatment has demonstrated therapeutic efficacy in pediatric retinal diseases, including retinopathy of prematurity, Coats disease, incontinentia pigmenti, and familial exudative vitreoretinopathy . Anti-VEGF treatment can be used as a primary treatment or adjunct therapy .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Intra-Anterior Chamber Injection of Ranibizumab in Advanced Pediatric Vitreoretinal Diseases

Zhang,

Liu,

Chen

et al. 2024

JAMA Ophthalmol

Self Cite

View full text Add to dashboard Cite

ImportanceAnti–vascular endothelial growth factor (VEGF) treatment through intravitreal or subretinal administrations has been proven effective for VEGF-driven pediatric vitreoretinal diseases but are not feasible for advanced cases, such as shallow traction retinal detachments or peripheral circumferential retinal detachments which adhere to the lens. Intra-anterior chamber injection (IAcI) of anti-VEGF may be a viable alternative in such cases but needs evaluation.ObjectiveTo investigate the effects and safety of IAcI of anti-VEGF to treat VEGF-driven pediatric vitreoretinal diseases.Design, Setting, and ParticipantsThis was a retrospective observational case series study conducted at Xinhua Hospital, affiliated with Shanghai Jiao Tong University School of Medicine in China. The study included 14 eyes of 13 children diagnosed with vitreoretinal disease exhibiting elevated vascular activity between January and August 2023.InterventionIAcI with ranibizumab.Main Outcomes and MeasuresRetinal vascular abnormalities, vitreous hemorrhage resolution, and complications 1 month and 3 months after injection.ResultsOf 13 patients included in this study, 12 were male. The mean age was 4.6 years (range, 1 month to 9 years). Six patients were diagnosed with familial exudative vitreoretinopathy, 4 with morning glory syndrome, 1 with retinopathy of prematurity, and 2 with chronic retinal detachments of unknown causes. At 1-month postoperative follow-up, vascular activity had decreased in 14 of 14 eyes. At 3-month follow-up, vascular activity had resolved in 7 of 14 eyes, persisted in 6 of 14 eyes, and reactivated in 1 of 14 eyes. On final observation, no complications were reported.Conclusions and RelevanceThese findings support the possibility of treatment using IAcI with ranibizumab to decrease retinal vascular abnormalities in familial exudative vitreoretinopathy or retinopathy of prematurity or related conditions, but further studies are needed to understand more precise benefits and risks. This approach might be considered in cases where intravitreal or subretinal injection are not feasible, recognizing the limitations of these findings and that longer-term outcomes still need to be monitored.

show abstract

Familial Exudative Vitreo-Retinopathy

Agarwal

Jalali

2023

Pediatric Vitreoretinal Surgery

View full text Add to dashboard Cite

Intravitreal Ranibizumab Treatment for Advanced Familial Exudative Vitreoretinopathy With High Vascular Activity

Cited by 5 publications

References 26 publications

Application of sensors for civil aircraft inerting system performance flight test

Application of sensors for civil aircraft inerting system performance flight test

Intra-Anterior Chamber Injection of Ranibizumab in Advanced Pediatric Vitreoretinal Diseases

Familial Exudative Vitreo-Retinopathy

Contact Info

Product

Resources

About