Intravoxel Incoherent Motion in Normal Pituitary Gland: Initial Study with Turbo Spin-Echo Diffusion-Weighted Imaging

Kamimura, Kiyohisa; Nakajo, Masanori; Fukukura, Yoshihiko; Iwanaga, Takashi; Saito, Tomonori; Sasaki, Makoto; Fujisaki, Takuro; Takemura, Akihiro; Okuaki, Tomoyuki; Yamada, Takashi

doi:10.3174/ajnr.a4930

Cited by 12 publications

(7 citation statements)

References 21 publications

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“…Measurement of precise SNR in DWI after application of distortion correction is complicated; in the present study, however, RDC-DWI provided images with high SNR, whereas in previous studies, no DWI technique has achieved SNR higher than that of conventional EPI-DWI [ 8 , 10 , 12 , 26 ]. Furthermore, compared with previously reported DWI techniques with distortion reduction, slice thickness of 1.2 mm in RDC-DWI resulted in higher spatial resolution with distortion correction and enabled observation from multiple directions using multiplanar reconstruction of the pituitary lesion and surrounding normal structures [ 7 , 8 , 10 – 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…The acquisition time for thin-slice RDC-DWI was 4:15 min:s. Scan times were also long in previously reported advanced DWI techniques for the pituitary region, such as line-scan DWI [ 8 ], periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER)/BLADE DWI [ 9 , 10 ], turbo-spin-echo (TSE) DWI [ 12 , 13 ], and readout-segmented EPI-DWI [ 14 , 15 ], although parameters such as slice thickness, number of slices, field of view, and number of excitations were different from RDC-DWI. Scan time is longer for RDC-DWI than conventional EPI-DWI but is clinically acceptable considering the clinical usefulness of RDC-DWI in the pituitary region, as shown in this study.…”

Section: Discussionmentioning

confidence: 99%

“…Echo-planar imaging-based DWI (EPI-DWI) is the most widely used DWI technique but is prone to geometric distortion along the phase-encoding direction due to B 0 field inhomogeneity, especially in the pituitary region [ 6 ]. To overcome image degradation due to distortion in the pituitary region, various DWI techniques, including single-shot fast spin-echo DWI [ 7 ], line-scan DWI [ 8 ], periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER)/BLADE DWI [ 9 , 10 ], reduced-field of view DWI [ 11 ], turbo-spin-echo (TSE) DWI [ 12 , 13 ], and readout-segmented EPI-DWI [ 14 , 15 ], have been developed. Nevertheless, the long acquisition time and low signal-to-noise ratio (SNR) of these techniques prevent their clinical application [ 10 , 12 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

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Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures

Ito,

Okuchi,

Fushimi

et al. 2024

Eur Radiol Exp

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Background To evaluate the clinical usefulness of thin-slice echo-planar imaging (EPI)-based diffusion-weighted imaging (DWI) with an on-console distortion correction technique, termed reverse encoding distortion correction DWI (RDC-DWI), in patients with non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma. Methods Patients with non-functioning PitNET/pituitary adenoma who underwent 3-T RDC-DWI between December 2021 and September 2022 were retrospectively enrolled. Image quality was compared among RDC-DWI, DWI with correction for distortion induced by B0 inhomogeneity alone (B0-corrected-DWI), and original EPI-based DWI with anterior-posterior phase-encoding direction (AP-DWI). Susceptibility artifact, anatomical visualization of cranial nerves, overall tumor visualization, and visualization of cavernous sinus invasion were assessed qualitatively. Quantitative assessment of geometric distortion was performed by evaluation of anterior and posterior displacement between each DWI and the corresponding three-dimensional T2-weighted imaging. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient values were measured. Results Sixty-four patients (age 70.8 ± 9.9 years [mean ± standard deviation]; 33 females) with non-functioning PitNET/pituitary adenoma were evaluated. In terms of susceptibility artifacts in the frontal and temporal lobes, visualization of left trigeminal nerve, overall tumor visualization, and anterior displacement, RDC-DWI performed the best and B0-corrected-DWI performed better than AP-DWI. The right oculomotor and right trigeminal nerves were better visualized by RDC-DWI than by B0-corrected-DWI and AP-DWI. Visualization of cavernous sinus invasion and posterior displacement were better by RDC-DWI and B0-corrected-DWI than by AP-DWI. SNR and CNR were the highest for RDC-DWI. Conclusions RDC-DWI achieved excellent image quality regarding susceptibility artifact, geometric distortion, and tumor visualization in patients with non-functioning PitNET/pituitary adenoma. Relevance statement RDC-DWI facilitates excellent visualization of the pituitary region and surrounding normal structures, and its on-console distortion correction technique is convenient. RDC-DWI can clearly depict cavernous sinus invasion of PitNET/pituitary adenoma even without contrast medium. Key points • RDC-DWI is an EPI-based DWI technique with a novel on-console distortion correction technique. • RDC-DWI corrects distortion due to B0 field inhomogeneity and eddy current. • We evaluated the usefulness of thin-slice RDC-DWI in non-functioning PitNET/pituitary adenoma. • RDC-DWI exhibited excellent visualization in the pituitary region and surrounding structures. • In addition, the on-console distortion correction of RDC-DWI is clinically convenient. Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures

Ito,

Okuchi,

Fushimi

et al. 2024

Eur Radiol Exp

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“…As stated earlier, non-EP DWI have been proposed to be widely used at the skull base where it performs better than its echo-planar counterpart. Successful achievements being reported were that TSE has reached a higher diagnostic accuracy in detecting recurrent cholesteatoma (18,21) and has potential value in the evaluation of the normal pituitary gland (30). The novel use of TSE-DWI for monitoring treatment response in active Grave's orbitopathy has been reported (31).…”

Section: Discussionmentioning

confidence: 99%

Potential value of non-echo-planar diffusion-weighted imaging of the nasopharynx: a primary study for differential diagnosis between recurrent nasopharyngeal carcinoma and post-chemoradiation fibrosis

et al. 2019

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Background Distinguishing recurrent nasopharyngeal carcinoma (rNPC) from post-therapeutic inflammatory changes remains a challenging clinical problem. Purpose To qualitatively and quantitatively evaluate image quality and compare the diagnostic value of non-echo-planar diffusion-weighted imaging (DWI) based on turbo spin-echo (TSE) and echo-planar imaging (EPI), to distinguish rNPC from post-chemoradiation fibrosis. Material and Methods Twenty-seven patients with newly diagnosed rNPC and 35 with biopsy-proven post-chemoradiation fibrosis were categorized into tumor and fibrosis groups, respectively. All patients underwent TSE and EP-DWI on a 3-T magnetic resonance unit. The image quality, lesion conspicuity, and distortions of the EPI and TSE images were qualitatively evaluated by two radiologists. The apparent diffusion coefficient values (ADCs), signal-to-noise ratios (SNRs), and contrast-to-noise ratios (CNRs) of the two sequences were also compared. Results The image quality scores indicated that TSE significantly improved image quality and reduced distortion of the nasopharyngeal lesions. Its SNR was slightly lower and CNR was significantly higher than those of EPI. The mean ADCs of the rNPC and post-chemoradiation fibrosis groups showed a significant difference in both sequences (P < 0.001). However, the ADCs of rNPC on EP-DWI showed a wide variation and more importantly, they appreciably overlapped with those of post-chemoradiation fibrosis. The area under the curve was 0.932 in TSE, which was significantly larger than 0.835 in EPI. Conclusions The images of nasopharyngeal lesions obtained with TSE-DWI were of better quality and higher diagnostic capability than those obtained with EP-DWI for differential diagnosis between rNPC and post-treatment sequelae.

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“…In the lung, magnetic inhomogeneity exists at the airlung interface, leading to signal loss or image distortion in EPI-DWI, which might hamper accurate lesion measurements of the derived parameters [3]. Turbo spinecho (TSE-) DWI might be an excellent alternative to EPI-DWI for patients sensitive to image distortion [4][5][6]. In recent years, studies [7][8][9] compared the image quality and the reproducibility of apparent diffusion coefficient (ADC) between EPI-DWI and TSE-DWI in areas such as oral, head, and neck.…”

Section: Introductionmentioning

confidence: 99%

Values of Apparent Diffusion Coefficient and Lesion-to-Spinal Cord Signal Intensity in Diagnosing Solitary Pulmonary Lesions: Turbo Spin-Echo versus Echo-Planar Imaging Diffusion-Weighted Imaging

Lei

Wan

Liu

et al. 2021

BioMed Research International

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Objective. This study is aimed at comparing the image quality and diagnostic performance of mean apparent diffusion coefficient (ADC) and lesion-to-spinal cord signal intensity ratio (LSR) derived from turbo spin-echo diffusion-weighted imaging (TSE-DWI) and echo-planar imaging- (EPI-) DWI in patients with a solitary pulmonary lesion (SPL). Methods. 33 patients with SPL underwent chest imaging using EPI-DWI and TSE-DWI with b = 600 s/mm2 in free breathing. A comparison of the distortion ratio (DR), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) was drawn between the two techniques using a Wilcoxon signed-rank test. The interprotocol reproducibility between quantitative parameters of EPI-DWI and TSE-DWI was evaluated using a Bland-Altman plot. ADCs and LSRs derived from EPI-DWI and TSE-DWI were calculated and compared between malignant and benign groups using the Mann–Whitney test. Results. TSE-DWI had similar SNR and CNR compared with EPI-DWI. DR was significantly lower on TSE-DWI than EPI-DWI. ADC and LSR showed slightly higher values with TSE-DWI, while the Bland-Altman analysis showed unacceptable limits of agreement between the two sequences. ADC and LSR of both DWI techniques differed significantly between lung cancer and benign lesions ( P < 0.05 ). The LSR(EPI-DWI) showed the highest area under the curve ( AUC = 0.818 ), followed by ADC(EPI-DWI) ( AUC = 0.789 ), ADC(TSE-DWI) ( AUC = 0.781 ), and LSR(TSE-DWI) ( AUC = 0.748 ), respectively. Among these parameters, the difference in diagnostic accuracy was not statistically significant. Conclusions. TSE-DWI provides significantly improved image quality in patients with SPL as compared with EPI-DWI. However, there was no difference in diagnostic efficacy between these two techniques, according to ADC and LSR.

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Intravoxel Incoherent Motion in Normal Pituitary Gland: Initial Study with Turbo Spin-Echo Diffusion-Weighted Imaging

Abstract: Our results demonstrated the feasibility of intravoxel incoherent motion assessment of the normal anterior pituitary lobe by using TSE-DWI. High D and f values in the anterior pituitary lobe were thought to reflect its microstructural and perfusion characteristics.

Cited by 12 publications

References 21 publications

Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures

Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures

Potential value of non-echo-planar diffusion-weighted imaging of the nasopharynx: a primary study for differential diagnosis between recurrent nasopharyngeal carcinoma and post-chemoradiation fibrosis

Values of Apparent Diffusion Coefficient and Lesion-to-Spinal Cord Signal Intensity in Diagnosing Solitary Pulmonary Lesions: Turbo Spin-Echo versus Echo-Planar Imaging Diffusion-Weighted Imaging

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