Intricate effects of post-translational modifications in liver cancer: mechanisms to clinical applications
Yu Zhang,
Weihao Xu,
Chuanhui Peng
et al.
Abstract:Liver cancer is a significant global health challenge, with hepatocellular carcinoma (HCC) being the most prevalent form, characterized by high incidence and mortality rates. Despite advances in targeted therapies and immunotherapies, the prognosis for advanced liver cancer remains poor. This underscores the urgent need for a deeper understanding of the molecular mechanisms underlying HCC to enable early detection and the development of novel therapeutic strategies. Post-translational modifications (PTMs) are … Show more
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