In general, the performance of productive systems considers the efficient use of technological transformation resources (such as machines and raw materials), information processing, and handling/transportation operations. However, there are no normalized criteria or rules to evaluate the performance of a productive system in the context of sustainability. Thus, this paper introduces an approach to identify and evaluate the performance indicators related to the sustainability of productive systems, specifically for geographically dispersed cases, i.e., dispersed productive system (DPS), in which the processes are in a distributed and dispersive architecture. The proposed approach is based on a framework aimed to measure sustainability key performance indicators (SuKPIs) that evaluate the sustainability of a system. The framework considers the ANSI/ISA-95 standard, and the sustainability assessment methodology considers the balance of sustainability indicators, which depend on economic, environmental, social, and technological aspects. The Petri net and derived techniques are used to model and to verify the main functionalities of the proposed framework, and also to monitor the productive processes of DPS for data acquisition of the SuKPIs. An application example is also presented to show the feasibility and validity of the proposal.