Wildlife crime, including poaching and wildlife trafficking, threaten the existence of particular species. To date, research on wildlife crime has been primarily conducted by those with backgrounds in the biological sciences, however crime scientists, have much to offer in examining wildlife crimes. With this in mind, we aim to highlight general principals of crime science found through an in-depth review of the conservation literature. More specifically, to determine if, and how, different types of wildlife crimes cluster, to identify the existence of interventions for which the mechanisms mirror those found within SCP, and consider their effectiveness. Our review suggests that various types of wildlife crimes concentrate in time and space, among products, along certain routes, and at particular facilities. Further, some overlap exists between mechanisms used to mitigate more traditional crimes and those used to prevent wildlife crimes and protect threatened species. Of note are the attempts by those in the conservation community to increase the risk of crime, remove excuses for non-compliance of rules, and reduce provocations that contribute to particular types of wildlife crime. Given this overlap crime scientists may be able to collaborate with conservationists to draw on the extensive knowledge base of prevention studies to identify potential interventions, analyze their implementation, and evaluate the overall impact of an intervention.