ObjectivesSexual violence against women is pervasive in India. Most of this violence is experienced in the context of marriage, and rates of marital sexual violence (MSV) have been relatively stagnant over the past decade. This paper machine learning algorithms paired with qualitative thematic analysis to identify new and potentially modifiable factors influencing MSV in India.Design, setting and participantsThis cross-sectional analysis of secondary data used data from in-person interviews with ever-married women aged 15–49 who responded to gender-based violence questions in the nationally representative 2015–2016 National Family Health Survey (N=66 013), collected between 20 January 2015 and 4 December 2016. Analyses included iterative thematic analysis (L-1 regularised regression followed by iterative qualitative thematic coding of L-2 regularised regression results) and neural network modelling.Outcome measureParticipants reported their experiences of sexual violence perpetrated by their current (or most recent) husband in the previous 12 months. These responses were aggregated into any vs no recent MSV.ResultsNearly 7% of women experienced MSV in the past 12 months. Major themes associated with MSV through iterative thematic analysis included experiences of/exposure to violence, sexual behaviour, decision making and freedom of movement, sociodemographics, access to media, health knowledge, health system interaction, partner control, economic agency, reproductive and maternal history, and health status. A neural network model identified variables that largely corresponded to these themes.ConclusionsThis analysis identified several themes that may be promising avenues to identify and support women experiencing MSV, and to mitigate these traumatic experiences. In particular, amplifying screening activities at health encounters, especially among women who appear to have compromised health or restricted agency, may enable a greater number of women access to essential physical and emotional support services, and merits further consideration.