The intellectual tension between the virtues of basic versus applied research that characterized an earlier era of psychology is being replaced by an appreciation of creative applications of all research essential to improving the quality of human life. Psychologists are positioned to "give psychology away" to all those who can benefit from our wisdom. Psychologists were not there 35 years ago when American Psychological Association (APA) President George Miller first encouraged us to share our knowledge with the public. The author argues that psychology is indeed making a significant difference in people's lives; this article provides a sampling of evidence demonstrating how and why psychology matters, both in pervasive ways and specific applications. Readers are referred to a newly developed APA Web site that documents current operational uses of psychological research, theory, and methodology (its creation has been the author's primary presidential initiative): www.psychologymatters.org.