Introduction

Dougherty, Thomas J.

doi:10.1002/lsm.20366

Cited by 3 publications

(2 citation statements)

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“…He discovered that it might be used as a photosensitizer to eradicate tumour tissue after using it as a tumour identification tool [12]. Dougherty rediscovered fluorescein diacetate's ability to photodynamically kill TA-3 cells in vitro in the 1970s [13].…”

Section: Introductionmentioning

confidence: 99%

Magnetite-silica core-shell nanostructures: Application for photodynamic therapy

Kaur,

Singh,

Jindal

2024

E3S Web Conf.

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Magnetite nanoparticles have been synthesized with chemical co-precipitation. The surface of magnetite nanoparticles was coated with an inorganic silica layer by hydrolyzing and condensing tetraethyl orthosilicate. An XRD investigation supports the cubic inverse spinel structure of Fe3O4 nanoparticles. The average crystallite size of the magnetite nanoparticles produced by the peak broadening was 13 nm. The UV-visible spectrum of methylene blue-loaded magnetite-silica nanoparticles shows a strong hump at 657 nm. According to TEM examination, the nanoparticles are polydisperse and almost spherical in form.The average size of the nanoparticles is 14.39 nm plus 1.66 nm, and they have a polydispersity index of 0.12%.The size and shape of the core-shell particles are not uniform, according to a SEM examination. There is no distinguishing morphology in any sample.The magnetic results depicts the superparamagnetic behaviour of nanoparticlesmakes them suitable for photodynamic therapy.

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Section: Introductionmentioning

confidence: 99%

Magnetite-silica core-shell nanostructures: Application for photodynamic therapy

Kaur,

Singh,

Jindal

2024

E3S Web Conf.

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“…Antimicrobial photodynamic therapy or photodynamic inactivation (PDI) has been reported as a promising option for inactivating oral microorganisms, particularly those resistant to conventional antibiotics and antifungal medications [16–21].…”

Section: Introductionmentioning

confidence: 99%

Liquid crystal precursor system as a vehicle for curcumin‐mediated photodynamic inactivation of oral biofilms

Reina

Santezi²,

Malheiros

et al. 2022

Journal of Biophotonics

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Curcumin has great potential as a photosensitizer, but it has low solubility in aqueous solutions. This study reports the antimicrobial efficacy of photodynamic inactivation (PDI) mediated by a curcumin‐loaded liquid crystal precursor (LCP) on in situ dental biofilms. Thirty volunteers used intraoral devices containing enamel samples for 48 hours for biofilm formation. The samples were then removed from the device and treated either with LCP with 160 μM of curcumin plus illumination at 18 J/cm2 (C + L+ group) or with LCP without curcumin in the dark (C – L − group). Following this, the biofilm from the samples was plated for quantifying the viable colonies at 37°C for 48 hours. Specific and nonspecific media were used for the presumptive isolation of Streptococcus mutans, Lactobacillus species/aciduric microorganisms, Candida species, and total microbiota. The C + L+ group showed a highly significant (P < .001) reduction in the log10 (colony forming units/mL) values as compared to the C − L − group for all culture media. Hierarchical linear regression indicated that there may be predictors at individual volunteer level explaining the difference in the PDI efficacy among different individuals (P = .001). The LCP system retained curcumin and released it slowly and continuously, thus protecting the drug from photodegradation. LCP with curcumin is considered effective for the photoinactivation of dental biofilms, but the PDI efficacy may differ based on the host's individual characteristics.

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Metalloporphyrin loaded semiconducting polymer dots as potent photosensitizers via triplet-triplet energy transfer

Qian

Hou

Chen

et al. 2019

Journal of Photochemistry and Photobiology A: Chemistry

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Introduction

Cited by 3 publications

References 1 publication

Magnetite-silica core-shell nanostructures: Application for photodynamic therapy

Magnetite-silica core-shell nanostructures: Application for photodynamic therapy

Liquid crystal precursor system as a vehicle for curcumin‐mediated photodynamic inactivation of oral biofilms

Metalloporphyrin loaded semiconducting polymer dots as potent photosensitizers via triplet-triplet energy transfer

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