Introduction

Bacterioplankton is an important component of marine as well as fresh waters and accounts for a large fraction of the production of particulate matter in those ecosystems. The concept of bacteria as providers of essential nutrients in aquatic food webs has been raised most recently in relation to the utilization of bacteria as a food source in aquaculture food chains. This article represents a comprehensive review on the potential role of bacteria as a direct food source for aquaculture organisms. After studying shortly the analytical tools that can be applied to determine the uptake and assimilation of bacteria by higher trophic levels, it describes the bacterial loads that are found in closed and open aquaculture systems and elaborates on the composition of bacteria from a nutritional point of view. Next this study elaborates in more detail on the role of bacteria as food for the zooplankton groups used as live food in aquaculture hatcheries and for various groups of aquaculture target organisms, such as fish, crustaceans and especially bivalves. This includes an assessment of the specific uptake mechanisms of the different taxonomic groups of interest in relation to their efficiency to ingest bacteria. Finally, future research lines are suggested to elucidate the nutritional impact of the bacterial community in aquaculture systems and how to steer this in order to optimize the production.

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SLC6A1 and Neuropsychiatric Diseases: The Role of Mutations and Prospects for Treatment with Genome Editing Systems

Букина

Kondratyev

Kozin

et al. 2021

Neurochem. J.

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SLC6A1 (Solute Carrier Family 6 Member 1) is a gene encoding GAT1, the gamma-aminobutyric acid (GABA) transporter protein. GAT1 is responsible for GABA reuptake from the synaptic cleft and intercellular space. Mutations in the SLC6A1 gene can lead to impaired GABA regulation and are associated with epilepsy and a number of mental disorders. In this review, we discuss the role of GAT1 protein in GABAergic regulation and the association of mutations in SLC6A1 gene with epilepsy, autism spectrum disorders, intellectual disability, and schizophrenia, as well as prospects for their treatment with genome editing systems.

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Introduction

Cited by 5 publications

References 27 publications

Temperature-dependent functional response of the invasive Asian clam, Corbicula fluminea, feeding on natural phytoplankton

Temperature-dependent functional response of the invasive Asian clam, Corbicula fluminea, feeding on natural phytoplankton

Bacteria as food in aquaculture: do they make a difference?

SLC6A1 and Neuropsychiatric Diseases: The Role of Mutations and Prospects for Treatment with Genome Editing Systems

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