In this special issue, we seek explanations for international- and local-level variations in policy approaches to ‘irregularized humanitarian migrants’, who left their country of citizenship in hopes of finding protection abroad but do not, or no longer, hold a permanent legal status. We shed light on different policy responses and experiences across Europe, Africa, and the wider Middle East by drawing on a wide array of political systems and migration patterns and different groups of humanitarian migrants. We explore to what extent the outcomes of various policies and practices can be regarded as better and more durable solutions, defined as increasingly taking into account the interests of migrants and the communities they live in. Ultimately, we stress the importance of gaining deeper and more comprehensive understandings of the historically informed context-specific circumstances that irregularized humanitarian migrants find themselves in, as well as the patterns that we see emerging in the comparison of these cases.