This chapter delves into the pivotal role of biofertilizers as a sustainable solution in addressing the intertwined challenges of food security and nutrition. Biofertilizers, derived from beneficial microorganisms, offer a promising alternative to conventional chemical fertilizers, enhancing soil fertility, crop productivity, and overall ecosystem health. The abstract explores the multifaceted benefits of biofertilizers in bolstering agricultural yields, improving soil health, and fostering nutrient-rich crops, consequently contributing to a more resilient and nourishing global food system. Additionally, it examines the hurdles and opportunities in widespread adoption, emphasizing the necessity for continued research, technological innovation, and comprehensive educational initiatives to maximize their potential impact on sustainable agriculture and human nutrition.