Introduction to animal antimicrobial use data collection in the United States: Methodological options

DeVincent, Stephen J.; Viola, Christina

doi:10.1016/j.prevetmed.2005.09.007

Cited by 6 publications

(3 citation statements)

References 6 publications

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“…43,136 Monitoring of veterinary antibiotic use, potentially including manufacturing, sales, distribution, prescribing, and administration data, has been highlighted as an area of importance for risk assessment of emerging antibiotic resistance in human pathogens. 137,138 In livestock, prolonged oral administration of broad-spectrum antibiotics and inadvertent under dosing increase the risk of emergence of antibiotic resistance that can then be passed to human pathogens. 139 Comprehensive veterinary prescription surveillance systems exist in the Netherlands and Nordic countries (Denmark, Finland, Norway, and Sweden).…”

Section: Risk Of Infections and Outbreaksmentioning

confidence: 99%

Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread

Clements

Magalhães

Tatem

et al. 2010

The Lancet Infectious Diseases

183

133

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Highly virulent strains of Clostridium difficile have emerged since 2003, causing large outbreaks of severe, often fatal, colitis in North America and Europe. In 2008-10, virulent strains spread between continents, with the first reported cases of fluoroquinolone-resistant C difficile PCR ribotype 027 in three Asia-Pacific countries and Central America. We present a risk assessment framework for assessing risks of further worldwide spread of this pathogen. This framework first requires identification of potential vehicles of introduction, including international transfers of hospital patients, international tourism and migration, and trade in livestock, associated commodities, and foodstuffs. It then calls for assessment of the risks of pathogen release, of exposure of individuals if release happens, and of resulting outbreaks. Health departments in countries unaffected by outbreaks should assess the risk of introduction or reintroduction of C difficile PCR ribotype 027 using a structured risk-assessment approach.

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Section: Risk Of Infections and Outbreaksmentioning

confidence: 99%

Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread

Clements

Magalhães

Tatem

et al. 2010

The Lancet Infectious Diseases

183

133

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“…In particular, the emergence of resistance to antimicrobials classified by the World Health Organization (WHO) as critically important for human health, primarily fluoroquinolones and third-and fourth-generation cephalosporins, is a point of major concern. In response, international organizations such as the WHO and the World Organisation for Animal Health (Office International des Épizooties, OIE; Paris, France), as well as several national organizations worldwide (Wray and Gnanou, 2000), are vigorously engaged in developing programs intended to monitor the emergence of antimicrobial resistance and to decrease AMC (DeVincent and Viola, 2006). Over the last couple of years, the AMC in fattening pigs, poultry, and veal calves has been extensively studied worldwide (Dunlop et al, 1998;Vieira et al, 2011;Bos et al, 2013), including in Belgium (Callens et al, 2012;Pardon et al, 2012;Persoons et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Quantification of antimicrobial consumption in adult cattle on dairy herds in Flanders, Belgium, and associations with udder health, milk quality, and production performance

Stevens

Piepers

Supré³

et al. 2016

Journal of Dairy Science

108

141

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The main objective of this study was to quantify the (compound-specific) antimicrobial consumption (AMC) in adult cattle in a convenience sample of Flemish dairy herds. Antimicrobial consumption data were obtained between 2012 and 2013 by "garbage can audits" and expressed as antimicrobial treatment incidence (ATI), with the unit of the ATI being the number of defined daily doses animal (DDDA) used per 1,000 cow-days. Herds were stratified by DDDA into low-, medium-, and high-consuming herds to study the AMC per route of administration, and associations with parameters reflecting udder health, milk quality, and production performances were examined. The average ATI in adult dairy cattle for all compounds was 20.78 DDDA (per 1,000 cow-days). Large variation existed between herds (ranging from 8.68 to 41.62 DDDA). Fourth-generation cephalosporins were used most (4.99 DDDA), followed by penicillins (3.70 DDDA) and third-generation cephalosporins (2.95 DDDA). The average ATI of the critically important antimicrobials for human health (i.e., third- and fourth-generation cephalosporins and fluoroquinolones according to the World Organisation for Animal Health classification) was somewhat lower than the average ATI of the other antimicrobials (8.59 and 12.18 DDDA, respectively). The average ATI for intramammary treatment of (sub)clinical mastitis, for dry-cow therapy, and for systemically administered antimicrobials was 6.30, 6.89, and 7.44 DDDA, respectively. In low-consuming herds, most antimicrobials were being used for dry-cow therapy, whereas in high-consuming herds, most antimicrobials were being used as injectable or intramammary mastitis therapy. The incidence rate of treated mastitis was positively associated with ATI. Herds that applied blanket dry-cow therapy tended to have a higher ATI than herds in which cows were selectively dried off with long-acting antimicrobials. The ATI decreased with an increasing prevalence of primiparous cows.

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“…Considerable care is often given to companion animals in order to prevent them from catching infections. For this purpose, several antibiotics including polymyxin are regularly administered as prophylaxis to pets, including those that are also authorized for human use [5]. Antibiotics are widely considered to be the most effective treatment for bacterial infections in pets; hence, their loss of efficacy can result in serious therapeutic difficulties for animals and humans [6].…”

Section: Introductionmentioning

confidence: 99%

Mobile Colistin Resistance (mcr) Genes in Cats and Dogs and Their Zoonotic Transmission Risks

et al. 2022

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Background: Pets, especially cats and dogs, represent a great potential for zoonotic transmission, leading to major health problems. The purpose of this systematic review was to present the latest developments concerning colistin resistance through mcr genes in pets. The current study also highlights the health risks of the transmission of colistin resistance between pets and humans. Methods: We conducted a systematic review on mcr-positive bacteria in pets and studies reporting their zoonotic transmission to humans. Bibliographic research queries were performed on the following databases: Google Scholar, PubMed, Scopus, Microsoft Academic, and Web of Science. Articles of interest were selected using the PRISMA guideline principles. Results: The analyzed articles from the investigated databases described the presence of mcr gene variants in pets including mcr-1, mcr-2, mcr-3, mcr-4, mcr-5, mcr-8, mcr-9, and mcr-10. Among these articles, four studies reported potential zoonotic transmission of mcr genes between pets and humans. The epidemiological analysis revealed that dogs and cats can be colonized by mcr genes that are beginning to spread in different countries worldwide. Overall, reported articles on this subject highlight the high risk of zoonotic transmission of colistin resistance genes between pets and their owners. Conclusions: This review demonstrated the spread of mcr genes in pets and their transmission to humans, indicating the need for further measures to control this significant threat to public health. Therefore, we suggest here some strategies against this threat such as avoiding zoonotic transmission.

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Introduction to animal antimicrobial use data collection in the United States: Methodological options

Cited by 6 publications

References 6 publications

Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread

Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread

Quantification of antimicrobial consumption in adult cattle on dairy herds in Flanders, Belgium, and associations with udder health, milk quality, and production performance

Mobile Colistin Resistance (mcr) Genes in Cats and Dogs and Their Zoonotic Transmission Risks

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