Introduction to Obesity

Lynn, William; Agrawal, Sanjay

doi:10.1007/978-3-030-54064-7_1-1

Obesity, Bariatric and Metabolic Surgery 2021

DOI: 10.1007/978-3-030-54064-7_1-1

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Introduction to Obesity

William Lynn

Sanjay Agrawal

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2023

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Leptin and Obesity: Understanding the Impact on Dyslipidemia

Rangareddy,

Venkatapathappa,

Mandalaneni

et al. 2023

Body Mass Index - Overweight, Normal Weight, Underweight

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Leptin, a hormone produced by fat cells, regulates energy balance and body weight by suppressing appetite and increasing energy expenditure. In obesity, there is often leptin resistance, reducing the hormone’s effects due to factors such as inflammation and changes in leptin receptors. This resistance leads to an increased risk of weight gain and obesity. Leptin therapy shows promise in treating obesity and related metabolic disorders, such as dyslipidemia and type 2 diabetes mellitus. It can lower body weight, improve insulin sensitivity, and reduce blood glucose and lipid levels. However, its effectiveness may be limited by the development of leptin resistance. Leptin also exhibits anti-inflammatory and cardiovascular protective effects, with potential therapeutic value for obesity-related conditions. Nevertheless, further research is necessary to comprehend leptin’s mechanisms and develop safe and effective therapies for these conditions, including those targeting dyslipidemia.

show abstract

Leptin and Obesity: Understanding the Impact on Dyslipidemia

Rangareddy,

Venkatapathappa,

Mandalaneni

et al. 2023

Body Mass Index - Overweight, Normal Weight, Underweight

View full text Add to dashboard Cite

show abstract

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Introduction to Obesity

Cited by 1 publication

References 53 publications

Leptin and Obesity: Understanding the Impact on Dyslipidemia

Leptin and Obesity: Understanding the Impact on Dyslipidemia

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