Introduction to spray drying

Anandharamakrishnan, C.; Ishwarya, S. Padma

doi:10.1002/9781118863985.ch1

Cited by 9 publications

(1 citation statement)

References 62 publications

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“…SEM micrograph showed slight change in spherical geometry of the microspheres after loading of LA and ATR in PLGA. This change is probably the result of the increase in viscosity of solution which produced large droplets after atomization (Paudel et al, 2013), since a high viscous feed is difficult to be broken down into tiny particles (Anandharamakrishnan and Ishwarya, 2015). In another investigation, in vitro study described a fast release of LA from microspheres, whereas for ATR, the release was slow.…”

Section: Encapsulation Techniques For Lamentioning

confidence: 99%

Recent developments in encapsulation of α-lipoic acid for enhanced bioavailability and stability

Choudhary

Dutta²,

Moses³

et al. 2023

Qual. Assur. Saf. Crops Foods

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α-lipoic acid (LA) is a potent antioxidant available in various plant and animal sources. Of late, there is high market demand for LA-based nutraceuticals, owing to enhanced occurrences of oxidative stress-based diseases. However, the effectiveness of LA is challenged with its low solubility, less stability, and low bioavailability. In addition, the unpleasant taste of LA limits its applications in food systems. In this context, encapsulation techniques can modify the chemical and biological properties of LA and improve its solubility and stability in the aqueous medium, which in turn helps in the development of different innovative therapeutic products based on LA. Different encapsulation techniques such as inclusion complexes, spray drying, electrospraying, solid lipid nanoparticles (SLN), emulsification, and liposomes have been explored for the encapsulation of LA. This review focuses on the biological activities of LA in terms of antioxidant, antidiabetic, anticancer, and anti-inflammatory properties, and the scope of encapsulation to enhance these properties, as evidenced through in vitro and in vivo studies. Furthermore, this article will help researchers and industrialists to select the suitable encapsulation method based on their requirement for delivering LA to achieve its optimal therapeutic potential.

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Section: Encapsulation Techniques For Lamentioning

confidence: 99%