Emotion regulation (ER) is an important factor in resilience and overall well-being throughout development, and youth report increased variation in emotion and capacity for regulation across adolescence and early adulthood. Specific emotions may be associated with the use of different ER strategies, but much evidence exclusively collapses across negative and positive affect or may not reflect the daily experience of emotion and emotion regulation. The present study examined associations between the experience of unique positive and negative emotions and the use of common ER strategies in adolescence and early adulthood during daily life using ecological momentary assessment (EMA). The sample included 184 high school and college students (55% female, M age = 17.88, SD = 1.25) who completed EMA surveys three times daily for 10 days (89% compliance). Participants reported on their recent emotional states and which of eight ER strategies they had used. Multilevel logistic regressions tested emotions as predictors of ER strategies, separately for each emotion-ER strategy combination across 96 total models, using the Benjamini-Hochberg procedure to control the false discovery rate. Individuals had higher odds of engaging in maladaptive ER strategies, particularly suppression or rumination, when reporting most types of negative emotions-with the largest associations among unhappiness and anger. Conversely, positive emotions were generally linked to reported use of no ER strategies, though happiness and engagement were related to higher odds of problem-solving, while calm was related to less use of nearly all strategies. Specific emotion-strategy combinations may have implications for clinical targets.