Intussusception among Japanese children: an epidemiologic study using an administrative database

Abstract

BackgroundThe epidemiology of intussusception, including its incidence, can vary between different countries. The aim of this study was to describe the epidemiology of childhood intussusception in Japan using data from a nationwide inpatient database.MethodsWe screened the database for eligible cases ≤ 18 years of age, who were coded with a discharge diagnosis of intussusception (International Classification of Diseases, 10th revision: K-561) between July to December in 2007 and 2008. We then selected cases according to Level 1 of the diagnostic certainty criteria developed by the Brighton Collaboration Intussusception Working Group. We examined the demographics, management, and outcomes of cases, and estimated the incidence of intussusception.ResultsWe identified 2,427 cases of intussusception. There were an estimated 2,000 cases of infantile intussusception annually in Japan, an incidence of 180-190 cases per 100,000 infants. The median age at diagnosis was 17 months, and two-thirds of the patients were male. Treatment with an enema was successful in 93.0% of cases (2255/2427). The remainder required surgery. Secondary cases accounted for 3.1% (76/2427). Median length of hospital stay was 3 days. Of the 2,427 cases, we found 2 fatal cases associated with intussusception.ConclusionsThis is currently the largest survey of childhood intussusception in Asia using a standardized case definition. Our results provide an estimate of the baseline risk of intussusception in Japan, and it is higher than the risk observed in other countries.

Risk factors for pediatric intussusception complicated by loss of intestine viability in China from June 2009 to May 2014: a retrospective study

“…Recent analyses of childhood intussusception in western countries [13,16,17] have found that the peak age was between 4 and 9 months; the male:female ratio was around 2:1 and PLPs were found in 2.6-15 % of cases, which is essentially consistent with our findings. Our result that the age of pediatric intussusception patients with loss of intestine viability was not significant is in accordance with one earlier study showing that intussusception-associated complications occurred irrespective of patient age [18].…”

Invagination intestinale aiguë du nourrisson et de l’enfant

“…Elles représentent moins de 10 % des IIA [10,23,37] mais leur fréquence augmente avec l'âge de l'enfant [10] et sont favorisées par une cause locale, une maladie générale ou un contexte particulier.…”

“…La surveillance après réduction, pour s'assurer de l'absence de récidive, est effectuée durant une hospitalisation dont la durée varie d'une demi-journée [90] à 48 heures selon les centres [37]. La réalimentation se fera en fonction de la symptomatologie initiale.…”

“…En cas de réduction impossible sans risque de déchirure de l'intestin ou des mésos, il faut pratiquer une résection anastomose en respectant, si possible, la valvule de Bauhin. Le taux de résection anastomose est important (30 %) dans de nombreuses séries, notamment dans les hôpitaux non spécialisés [10,37].…”

“…Actuellement, dans les pays développés, le taux de mortalité de cette affection oscille entre 0 et 1 % [8,28,31,37,100]. La mortalité est liée le plus souvent à un retard diagnostique ou thérapeutique [29] mais peut être également due à la pathologie responsable de l'invagination dans les formes secondaires.…”