Intussusception due to inflammatory fibroid polyps of the ileum: A report of 12 cases from Africa

Abstract

Eleven cases of inflammatory fibroid polyp of the ileum from Malawi and 1 from Sierra Leone are described. All 12 patients presented with acute intestinal obstruction as a result of an intussusception caused by the polyp. The lesions are characterized by a variable proliferation of fibroblasts and small vessels which may involve the whole thickness of the bowel wall. Tissue mast cells and eosinophils were noted in the polyps. The aetiology of these lesions remains obscure but they appear to be reactive rather than neoplastic. The condition appears to occur more commonly in Malawi than in the United Kingdom or North America and is an important cause of small bowel obstruction in that part of Africa.

Ileal Intussusception Caused by Vanek’s Tumor: A Case Report

“…Benign tumors as the lead points of intussusceptions have been found to include lipomas, leiomyomas, neurofibromas, adenomas, and more rarely IFPS [3, 12]. Sixty-five percent of all adult intussusceptions occur due to a malignant or benign lesion usually appearing at the head of the invagination [3].…”

“…The involvement of the small intestine and colon by IFPs is rare. Patients with IFPs located on the small bowel usually present with episodes of relapsing abdominal colics and intermittent episodes of intestinal bowel intussusceptions [3, 4, 5, 6, 7, 8]. Although malignant diseases represent the major causes of intussusceptions in adults, there are few reports of intestinal obstruction and perforation caused by IFPs [3, 4, 7, 8].…”

Late Postoperative Partial Recurrent Retrograde Ileoileal Intussusception

“…Otlier causes mentioned in the literature include polyps, adenoma, carcinoma, inverted Meckel's diverticulum, 6 submucosal lipoma, 7 lymphoma (including Burkitt's lymphoma, whose intestinal type is more common in Iraq than the faciomaxillary type), lymphoid hyperplasia (usually of Peyer's patches), submucosal or intramural hematoma in association with Henoch-Schoenlein purpura or abdominal injury. 8 Adult intussusception may also be attributable to inflammatory lesions including inflammatory fibroid polyps, 9 ascariasis, cystic fibrosis, celiac disease, fibroma, intestinal duplication, inverted appendix, enterogenic cyst, granulomas (including amebic granulomas which are not uncommon in Iraq), 7 a nodule of ectopic pancreas, a foreign body, and iatrogenic lesions (as from long intestinal tubes). 10 Any of these lesions could initiate the telescoping process by acting as a leading point.…”

An Inflammatory Fibroid Polyp (Vanek’s Tumor) of the Ileum that Presented as Intussusception

“…Sixty-five percent of all adult intussusceptions occur because of a malignant or a benign lesion, usually appearing at the head of the invagination [9]. Malignant causes are found in 43% to 80% of intussusceptions located in the colon compared to approximately 14% to 47% of cases occurring in the small intestine.…”